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6.3.2.23: homoglutathione synthase

This is an abbreviated version!
For detailed information about homoglutathione synthase, go to the full flat file.

Word Map on EC 6.3.2.23

Reaction

ATP
+
gamma-L-glutamyl-L-cysteine
+
beta-Alanine
=
ADP
+
phosphate
+
gamma-L-glutamyl-L-cysteinyl-beta-alanine

Synonyms

beta-alanine specific hGSH synthetase, hGS, hGSH synthetase, hGSH-synthetase, hGSHS, homoglutathione synthetase, synthetase, homoglutathione

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.23 homoglutathione synthase

KM Value

KM Value on EC 6.3.2.23 - homoglutathione synthase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.023 - 0.45
ATP
0.33 - 24.8
beta-Alanine
8.3
gamma-aminobutyrate
-
-
0.073 - 0.75
gamma-glutamylcysteine
0.044
gamma-L-glutamyl-L-cysteine
-
-
2.2 - 104
glycine
additional information
additional information
-
glycine, value above 100 mM, wild-type enzyme
-