6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase

This is an abbreviated version!
For detailed information about UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase, go to the full flat file.

Word Map on EC 6.3.2.13

6.3.2.13

ligases

d-glutamic

methicillin

pgsbca

Reaction

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate

Synonyms

amide ligase, Diaminopimelic-adding enzyme, mDAP ligase, Meso-diaminopimelate-adding enzyme, Mur ligase, MurE, MurE synthetase, MurEEr, peptidoglycan MurE ligase, Synthetase, uridine diphospho-N-acetylmuramoylalanyl-D-glutamyl-meso-2,6-diaminopimelate, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase, UDP-N-acetylmuramyl tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase, UDPMurNAc-L-alanyl-D-glutamate:mDAP ligase (ADP-forming), Uridine diphosphate N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase, Uridine-diphosphate-N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate synthetase

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.2 Acid—amino-acid ligases (peptide synthases)

6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
32413	AA Sequence
1	CAS Registry Number
11	Cloned(Commentary)
3	Cofactor
4	Crystallization (Commentary)
7	General Information
13	IC50 Value
27	Inhibitors
8	kcat/KM [mM/s]
57	KM Value [mM]
13	Localization
23	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
38	Organism
7	Pathway
42	PDB ID
9	pH Optimum
2	pH Range
16	Protein Variants
11	Purification (Commentary)
3	Reaction
3	Reaction Type
31	Reference
6	Source Tissue
9	Specific Activity [micromol/min/mg]
2	Storage Stability
82	Substrates and Products (Substrate)
2	Subunits
35	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
15	Turnover Number [1/s]

KM Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KM Value on EC 6.3.2.13 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to KM Value Search

0.008 - 3.6

ATP

13 entries

D-allo-cystathionine

Escherichia coli

1038

1.7

D-Lysine

Thermotoga maritima

at 68°C

674565

0.097

dihydrouridine-5'-diphosphate-MurNAc-L-Ala-D-Glu

Escherichia coli

1027

1.8 - 64

L-alanine

2 entries

3.9

L-allo-cystathionine

Escherichia coli

1038

2.8

L-lysine

at 68°C

L-ornithine

at 68°C

0.012 - 77

meso-2,6-diaminoheptanedioate

12 entries

0.069 - 4.8

meso-diaminopimelic acid

3 entries

1.5

meso-lanthionine

Escherichia coli

1038

0.005 - 0.148

UDP-MurNAc-L-Ala-D-Glu

7 entries

0.23

UDP-N-acetyl-alpha-D-muramoyl-glycyl-D-glutamate

Erysipelothrix rhusiopathiae

E7FUC9

pH 9.6, 37°C, recombinant His-tagged enzyme

744440

0.16

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate

Erysipelothrix rhusiopathiae

E7FUC9

pH 9.6, 37°C, recombinant His-tagged enzyme

744440

0.21

UDP-N-acetyl-alpha-D-muramoyl-L-seryl-D-glutamate

Erysipelothrix rhusiopathiae

E7FUC9

pH 9.6, 37°C, recombinant His-tagged enzyme

744440

0.04

UDP-N-acetylmuramoyl-L-Ala-D-Glu

Mycobacterium tuberculosis

P9WJL3

pH 7.4, 37°C

716979

0.03 - 0.45

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

2 entries

0.035 - 0.32

UDP-N-MurNAc-L-Ala-D-Glu

3 entries