6.3.1.4: aspartate-ammonia ligase (ADP-forming)
This is an abbreviated version!
For detailed information about aspartate-ammonia ligase (ADP-forming), go to the full flat file.
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Synonyms
ASNS, Asparagine synthetase, Asparagine synthetase (adenosine diphosphate-forming), Asparagine synthetase (ADP-forming), Synthetase, asparagine (adenosine diphosphate-forming)
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Substrates Products
Substrates Products on EC 6.3.1.4 - aspartate-ammonia ligase (ADP-forming)
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REACTION DIAGRAM
ATP + L-Asp + hydroxylamine
ADP + phosphate + beta-aspartylhydroxamate
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maximal activity at 400 mM NH2OH
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additional information
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importance of ASNS protein in the cellular mechanisms that confer drug resistance upon the leukemic cells
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ADP + phosphate + L-Asn
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specific for L-Asp
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