6.3.1.17: beta-citrylglutamate synthase
This is an abbreviated version!
For detailed information about beta-citrylglutamate synthase, go to the full flat file.
Word Map on EC 6.3.1.17
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6.3.1.17
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n-acetylaspartylglutamate
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testis
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carboxypeptidase
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neuropeptide
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atp-grasp
- 6.3.1.17
- n-acetylaspartylglutamate
- testis
- carboxypeptidase
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neuropeptide
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atp-grasp
Reaction
Synonyms
GCP3, NAAG synthetase I, NAAGS-I, RIMKLB
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 6.3.1.17 - beta-citrylglutamate synthase
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REACTION DIAGRAM
ADP + phosphate + beta-citryl-L-glutamate
ATP + citrate + L-glutamate
isoform GCP3 acts preferentially on beta-citryl-L-glutamate in the presence of Ca2+. Its activity on this substrate is lower in the presence of Mn2+ and completely cancelled in the presence of Zn2+
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ADP + phosphate + N-acetyl-aspartylglutamate
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in the presence of Ca2+, the purified enzyme specifically hydrolyzes beta-citrylglutamate and does not act on N-acetyl-aspartylglutamate. However, both compounds were hydrolyzed in the presence of Mn2+
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ATP + citrate + L-glutamate
ADP + phosphate + beta-citryl-L-glutamate
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