6.2.1.8: oxalate-CoA ligase
This is an abbreviated version!
For detailed information about oxalate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.8
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6.2.1.8
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co2
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formyl-coa
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truncatula
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aluminum
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medicago
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sclerotinia
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knock-down
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sclerotiorum
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coping
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rnai
- 6.2.1.8
- co2
- formyl-coa
- truncatula
-
aluminum
-
medicago
-
sclerotinia
-
knock-down
- sclerotiorum
-
coping
- rnai
Reaction
Synonyms
AAE3, acyl activating enzyme3, acyl-activating enzyme 3, acyl-activating enzyme3, OCS, Oxalate:CoA ligase (AMP), Oxalyl CoA synthetase, Oxalyl coenzyme A synthetase, Oxalyl-CoA synthetase, ScAAE3, Synthetase, oxalyl coenzyme A
ECTree
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General Information
General Information on EC 6.2.1.8 - oxalate-CoA ligase
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malfunction
metabolism
physiological function
a Scaae3 deletion mutant strain shows highly reduced oxalate degradation activity decreasing recovery from exposure to oxalate, e.g. by exposure to oxalate-secreting microbes, and to oxidative stress, e.g. by H2O2
malfunction
aae3 null mutants show increased soluble and insoluble oxalate contents compared to the wild-type enzyme, loss of AAE3 interferes with seed development affecting the integrity and function of the seed coat, phenotype, overview
malfunction
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reduction of enzyme expression increases susceptibility of Medicago truncatula to the oxalate-secreting fungal pathogen Sclerotinia sclerotiorum and results in the accumulation of druse crystals of calcium oxalate
malfunction
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a Scaae3 deletion mutant strain shows highly reduced oxalate degradation activity decreasing recovery from exposure to oxalate, e.g. by exposure to oxalate-secreting microbes, and to oxidative stress, e.g. by H2O2
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the enzyme catalyzes the first step in oxalate degradation
oxalyl-CoA synthetase is required for oxalate degradation, for normal seed development, and for defense against an oxalate-producing fungal pathogen, e.g. the fungus Sclerotinia sclerotiorum
physiological function
the enzyme catalyzes the first step in a pathway of oxalate degradation to protect the cell against the harmful effects of oxalate derived from an endogenous process or an environmental source
physiological function
enzyme-dependent degradation of oxalate is important for normal seed development and for defense against oxalate-producing fungal pathogens
physiological function
the enzyme is involved in aluminum tolerance
physiological function
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the enzyme catalyzes the first step in a pathway of oxalate degradation to protect the cell against the harmful effects of oxalate derived from an endogenous process or an environmental source
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