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6.2.1.7: cholate-CoA ligase

This is an abbreviated version!
For detailed information about cholate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.7

Reaction

ATP
+
cholate
+
CoA
=
AMP
+
diphosphate
+
choloyl-CoA

Synonyms

BAL, bile acid coenzyme A ligase, Bile acid coenzyme A synthetase, Bile acid-coenzyme A ligase, Bile acid:CoA ligase, CCL, Cholate thiokinase, Cholic acid:CoA ligase, Cholic thiokinase, Choloyl coenzyme A synthetase, Choloyl-CoA synthetase, EC 6.2.1.29, Synthetase, choloyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.7 cholate-CoA ligase

Reference

Reference on EC 6.2.1.7 - cholate-CoA ligase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Prydz, K.; Kase, B.F.; Bjoerkhem, I.; Pedersen, J.I.
Subcellular localization of 3alpha,7alpha-dihydroxy- and 3alpha,7alpha,12alpha-trihydroxy-5beta-cholastanoyl-coenzyme A ligase(s) in rat liver
J. Lipid Res.
29
997-1004
1988
Rattus norvegicus
Manually annotated by BRENDA team
Vessey, D.A.; Benfatto, A.M.; Zerweck, E.; Vestweber, C.
Purification and characterization of the enzymes of bile acid conjugation from fish liver
Comp. Biochem. Physiol. B
95
647-652
1990
Ophiodon elongatus, Sebastes miniatus, Sebastes pinniger
Manually annotated by BRENDA team
Mallonee, D.H.; Adams, J.L.; Hylemon, P.B.
The bile acid-inducible baiB gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A ligase
J. Bacteriol.
174
2065-2071
1992
Eubacterium sp., Eubacterium sp. VPI 12708
Manually annotated by BRENDA team
Kelley, M.; Vessey, D.A.
Determination of the mechanism of reaction for bile acid:CoA ligase
Biochem. J.
304
945-949
1994
Cavia porcellus
Manually annotated by BRENDA team
Schepers, L.; Casteels, M.; Verheyden, K.; Parmentier, G.; Asselberghs, S.; Eyssen, H.J.; Mannaerts, G.P.
Subcellular distribution and characteristics of trihydroxycoprostanoyl-CoA synthetase in rat liver
Biochem. J.
257
221-229
1989
Rattus norvegicus
Manually annotated by BRENDA team
Van Veldhoven, P.P.; Asselberghs, S.; Eyssen, H.J.; Mannaerts, G.P.
Stabilisation and partial purification of Triton X-100 solubilised trihydroxycoprostanoyl-CoA synthetase from rat liver
Biochem. Mol. Biol. Int.
40
447-457
1996
Rattus norvegicus
Manually annotated by BRENDA team
Kwakye, J.B.; Barnes, S.; Diasio, R.B.
Identification of bile acid coenzyme A synthetase in rat kidney
J. Lipid Res.
34
95-99
1993
Rattus norvegicus
Manually annotated by BRENDA team
Kelley, M.; Vessey, D.A.
Dual role of divalent cations in the bile acid:CoA ligase catalyzed reaction
Biochim. Biophys. Acta
1209
51-55
1994
Cavia porcellus
Manually annotated by BRENDA team
Vessey, D.A.; Benfatto, A.M.
Chemical modification of bile acid: CoA ligase
Biochim. Biophys. Acta
1203
126-130
1993
Cavia porcellus
Manually annotated by BRENDA team
Vessey, D.A.; Erdman, A.; Kelley, M.; Claire, T.St.
A coupled assay for bile acid:CoA ligase
Anal. Biochem.
195
97-100
1991
Cavia porcellus
Manually annotated by BRENDA team
Simion, F.A.; Fleischer, B.; Fleischer, S.
Subcellular distribution of cholic acid:Coenzyme A ligase and deoxycholic acid:coenzyme A ligase activities in rat liver
Biochemistry
22
5029-5034
1983
Rattus norvegicus
Manually annotated by BRENDA team
Lim, W.C.; Jordan, T.W.
Subcellular distribution of hepatic bile acid-conjugation enzymes
Biochem. J.
197
611-618
1981
Rattus norvegicus
Manually annotated by BRENDA team
Kirkpatrick, R.B.; Robinson,S.F.; Killenberg, P.G.
Diurnal variation of rat liver enzymes catalyzing bile acid conjugation and sulfation
Biochim. Biophys. Acta
620
627-630
1980
Rattus norvegicus
Manually annotated by BRENDA team
Polokoff, M.A.; Coleman, R.A.; Bell, R.M.
Evidence that cholic acid CoA ligase is located asymetrically on the cytoplasmic surface of hepatic microsomal vesicles
J. Lipid Res.
20
17-21
1979
Rattus norvegicus
Manually annotated by BRENDA team
Vessey, D.A.; Zakim, D.
Characterization of microsomal choloyl-coenzyme A synthetase
Biochem. J.
163
357-362
1977
Cavia porcellus
Manually annotated by BRENDA team
Polokoff, M.A.; Bell, R.M.
Characterization of liver cholic acid coenzyme A ligase activity. Evidence that separate microsomal enzymes are responsible for cholic acid and fatty acid activation
J. Biol. Chem.
252
1167-1171
1977
Rattus norvegicus
Manually annotated by BRENDA team
Mallonee, D.H.; White, W.B.; Hylemon, P.B.
Cloning and sequencing of a bile acid-inducible operon from Eubacterium sp. Strain VPI 12708
J. Bacteriol.
172
7001-7019
1990
Eubacterium sp., Eubacterium sp. VPI 12708
-
Manually annotated by BRENDA team
Östlund, A.K.; Nilsson, A.; Pedersen, J.I.
Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation
J. Lipid Res.
34
2041-2050
1993
no activity in Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Steinberg, S.J.; Mihalik, S.J.; Kim, D.G.; Cuebas, D.A.; Watkins, P.A.
The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate: CoA ligase
J. Biol. Chem.
275
15605-15608
2000
Homo sapiens
Manually annotated by BRENDA team
Wheeler, J.B.; Shaw, D.R.; Barnes, S.
Purification and characterization of a rat liver bile acid coenzyme A ligase from rat liver microsomes
Arch. Biochem. Biophys.
348
15-24
1997
Rattus norvegicus
Manually annotated by BRENDA team
Falany, C.N.; Xie, X.; Wheeler, J.B.; Wang, J.; Smith, M.; He, D.; Barnes, S.
Molecular cloning and expression of rat liver bile acid CoA ligase
J. Lipid Res.
43
2062-2071
2002
Rattus norvegicus
Manually annotated by BRENDA team
Hadzic, N.; Bull, L.N.; Clayton, P.T.; Knisely, A.S.
Diagnosis in bile acid-CoA: amino acid N-acyltransferase deficiency
World J. Gastroenterol.
18
3322-3326
2012
Homo sapiens
Manually annotated by BRENDA team