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6.2.1.7: cholate-CoA ligase

This is an abbreviated version!
For detailed information about cholate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.7

Reaction

ATP
+
cholate
+
CoA
=
AMP
+
diphosphate
+
choloyl-CoA

Synonyms

BAL, bile acid coenzyme A ligase, Bile acid coenzyme A synthetase, Bile acid-coenzyme A ligase, Bile acid:CoA ligase, CCL, Cholate thiokinase, Cholic acid:CoA ligase, Cholic thiokinase, Choloyl coenzyme A synthetase, Choloyl-CoA synthetase, EC 6.2.1.29, Synthetase, choloyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.7 cholate-CoA ligase

General Stability

General Stability on EC 6.2.1.7 - cholate-CoA ligase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
PMSF, 0.1 M, can counteract the inactivation of the enzyme at 4°C
-
the lability of the delipidated enzyme can be suppressed by high concentrations of polyols such as sucrose and glucose
-