6.2.1.45: E1 ubiquitin-activating enzyme

This is an abbreviated version, for detailed information about E1 ubiquitin-activating enzyme, go to the full flat file.

Reaction

ATP
+
ubiquitin
+
[E1 ubiquitin-activating enzyme]-L-cysteine
=
AMP
+
diphosphate
+
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine

Synonyms

E1, E1 ubiquitin-activating enzyme, HsUba1a, NEDD8-activating enzyme E1 catalytic subunit, SUMO E1, Ub E1 activating enzyme, Ub-activating ligase, Uba1, Uba1a, UBA1p, UBA2, Uba3, UBA5, Uba6, UBE1, UBE1DC1, UBE1DC1A, UBE1DC1B, UBE1L2, ubiquitin activating enzyme, ubiquitin activating enzyme 2, ubiquitin E1, ubiquitin protein ligase E1, Ubiquitin-activating enzyme, ubiquitin-activating enzyme (E1), ubiquitin-activating enzyme 1, ubiquitin-activating enzyme 5, ubiquitin-activating enzyme 6, ubiquitin-activating enzyme E1, ubiquitin-activating enzyme E1 domain-containing protein 1, ubiquitin-activating enzyme E1-domain containing 1, ubiquitin-activating enzyme, UBE1, ubiquitin-conjugating enzyme, ubiquitin-like modifier-activating enzyme 1, ubiquitin-like modifier-activating enzyme 5, ubiquitin-like modifier-activating enzyme 6

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.45 E1 ubiquitin-activating enzyme