6.2.1.42: 3-oxocholest-4-en-26-oate-CoA ligase

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For detailed information about 3-oxocholest-4-en-26-oate-CoA ligase, go to the full flat file.

Reaction

Synonyms

fadD19, steroid-CoA ligase

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.42 3-oxocholest-4-en-26-oate-CoA ligase

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50	AA Sequence
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8	General Information
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1	Metals/Ions
6	Natural Substrates/ Products (Substrates)
197	Organism
3	Pathway
2	Protein Variants
1	Purification (Commentary)
1	Reaction
6	Reference
14	Substrates and Products (Substrate)
11	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 6.2.1.42 - 3-oxocholest-4-en-26-oate-CoA ligase

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SYSTEMATIC NAME

IUBMB Comments

3-oxocholest-4-en-26-oate:CoA ligase (AMP-forming)

The enzyme, characterized from actinobacterium Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol. It is responsible for the activation of the C8 side chain. 3beta-hydroxycholest-5-en-26-oate can also be used as substrate.