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6.2.1.36: 3-hydroxypropionyl-CoA synthase

This is an abbreviated version!
For detailed information about 3-hydroxypropionyl-CoA synthase, go to the full flat file.

Reaction

3-hydroxypropanoate
+
ATP
+
CoA
=
3-hydroxypropanoyl-CoA
+
AMP
+
diphosphate

Synonyms

3-hydroxypropionyl-CoA synthetase (AMP-forming)

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.36 3-hydroxypropionyl-CoA synthase

Substrates Products

Substrates Products on EC 6.2.1.36 - 3-hydroxypropionyl-CoA synthase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-chloropropionate + ATP + coenzyme A
3-chloropropionyl-CoA + AMP + diphosphate
show the reaction diagram
3-hydroxypropanoate + ATP + coenzyme A
3-hydroxypropanoyl-CoA + AMP + diphosphate
show the reaction diagram
3-hydroxypropanoate + CTP + coenzyme A
3-hydroxypropanoyl-CoA + CMP + diphosphate
show the reaction diagram
13% of the activity with ATP
-
-
?
3-hydroxypropanoate + UTP + coenzyme A
3-hydroxypropanoyl-CoA + UMP + diphosphate
show the reaction diagram
32% of the activity with ATP
-
-
?
3-mercaptopropionate + ATP + coenzyme A
3-mercaptopropionyl-CoA + AMP + diphosphate
show the reaction diagram
acetate + ATP + coenzyme A
acetyl-CoA + AMP + diphosphate
show the reaction diagram
acrylate + ATP + coenzyme A
acryloyl-CoA + AMP + diphosphate
show the reaction diagram
butyrate + ATP + coenzyme A
butyryl-CoA + AMP + diphosphate
show the reaction diagram
propionate + ATP + coenzyme A
propionyl-CoA + AMP + diphosphate
show the reaction diagram
additional information
?
-