6.2.1.33: 4-chlorobenzoate-CoA ligase
This is an abbreviated version!
For detailed information about 4-chlorobenzoate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.33
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6.2.1.33
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dehalogenase
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4-hydroxybenzoate
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thioesterase
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amp
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half-reaction
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thioester-forming
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adenylate-forming
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thioesterification
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acyl-adenylate
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4-hydroxybenzoyl-coa
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homotetramer
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dehalogenation
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4-cba-coa
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single-turnover
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pantetheine
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aryl-coa
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alcaligenes
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diester
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chlorinate
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mgatp
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poised
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arthrobacter
- 6.2.1.33
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dehalogenase
- 4-hydroxybenzoate
-
thioesterase
- amp
-
half-reaction
-
thioester-forming
-
adenylate-forming
-
thioesterification
-
acyl-adenylate
- 4-hydroxybenzoyl-coa
-
homotetramer
-
dehalogenation
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4-cba-coa
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single-turnover
- pantetheine
- aryl-coa
- alcaligenes
-
diester
-
chlorinate
- mgatp
-
poised
-
arthrobacter
Reaction
Synonyms
4-CB:CoA ligase, 4-CBA:CoA ligase, 4-chlorobenzoate:CoA ligase, 4-Chlorobenzoate:coenzyme A ligase, 4-Chlorobenzoyl-CoA ligase, 4-Chlorobenzoyl-coenzyme A ligase, 4-Halobenzoate-coenzyme A ligase, CBAL, CBL, chlorobenzoate:CoA ligase, Synthetase, 4-chlorobenzoyl coenzyme A
ECTree
6.2.1.33 4-chlorobenzoate-CoA ligaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 6.2.1.33 - 4-chlorobenzoate-CoA ligase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
4-Chlorobenzoate + CoA + ADP
4-Chlorobenzoyl-CoA + AMP + phosphate
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reaction with ADP at 7.5% of the reaction with ATP
-
-
?
4-Methoxybenzoate + CoA + ATP
4-Methoxybenzoyl-CoA + AMP + diphosphate
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at 9% of the activity with 4-chlorobenzoate
-
-
?
4-Nitrobenzoate + CoA + ATP
4-Nitrobenzoyl-CoA + AMP + diphosphate
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at 7% of the activity with 4-chlorobenzoate
-
-
?
ATP + 4-chlorobenzoate + CoA
AMP + diphosphate + 4-chlorobenzoyl-CoA
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ATP in form of MgATP2-
-
-
?
4-Bromobenzoate + CoA + ATP
4-Bromobenzoyl-CoA + AMP + diphosphate
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93% of the activity with 4-chlorobenzoate
-
-
?
4-Bromobenzoate + CoA + ATP
4-Bromobenzoyl-CoA + AMP + diphosphate
-
93% of the activity with 4-chlorobenzoate
-
-
?
4-Bromobenzoate + CoA + ATP
4-Bromobenzoyl-CoA + AMP + diphosphate
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at 105% of the activity with 4-chlorobenzoate
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
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the enzyme catalyzes the synthesis of 4-chlorobenzoyl-CoA, the first step in the 4-chlorobenzoate degradation pathway in 4-chlorobenzoate-degrading bacteria
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
the rate-limiting step in CBL catalysis follows the formation of 4-chlorobenzoate-CoA
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
4-chlorobenzoyl-adenosine 5'-phosphate diester is formed by the first partial reaction
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
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negligible activity with UTP, CTP, and GTP
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
-
-
?
4-Chlorobenzoate + CoA + ATP
4-Chlorobenzoyl-CoA + AMP + diphosphate
-
4-chlorobenzoyl-adenosine 5'-phosphate diester is formed by the first partial reaction
-
-
?
4-Chlorobenzoate + CoA + ATP
?
-
catalyzes the first step in the 4-chlorobenzoate degradation pathway
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-
?
4-Chlorobenzoate + CoA + ATP
?
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induced by growth with 4-chlorobenzoate as sole carbon source
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-
?
4-Chlorobenzoate + CoA + ATP
?
-
catalyzes the first step in the 4-chlorobenzoate degradation pathway
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-
?
4-Fluorobenzoate + CoA + ATP
4-Fluorobenzoyl-CoA + AMP + diphosphate
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67% of the activity with 4-chlorobenzoate
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-
?
4-Fluorobenzoate + CoA + ATP
4-Fluorobenzoyl-CoA + AMP + diphosphate
-
67% of the activity with 4-chlorobenzoate
-
-
?
4-Fluorobenzoate + CoA + ATP
4-Fluorobenzoyl-CoA + AMP + diphosphate
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at 36% of the activity with 4-chlorobenzoate
-
-
?
4-Iodobenzoate + CoA + ATP
4-Iodobenzoyl-CoA + AMP + diphosphate
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73% of the activity with 4-chlorobenzoate
-
-
?
4-Iodobenzoate + CoA + ATP
4-Iodobenzoyl-CoA + AMP + diphosphate
-
73% of the activity with 4-chlorobenzoate
-
-
?
4-Iodobenzoate + CoA + ATP
4-Iodobenzoyl-CoA + AMP + diphosphate
-
at 90% of the activity with 4-chlorobenzoate
-
-
?
4-Methylbenzoate + CoA + ATP
4-Methylbenzoyl-CoA + AMP + diphosphate
-
-
-
?
4-Methylbenzoate + CoA + ATP
4-Methylbenzoyl-CoA + AMP + diphosphate
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at 22% of the activity with 4-chlorobenzoate
-
-
?
Benzoate + CoA + ATP
Benzoyl-CoA + AMP + diphosphate
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62% of the activity with 4-chlorobenzoate
-
-
?
Benzoate + CoA + ATP
Benzoyl-CoA + AMP + diphosphate
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at 5% of the activity with 4-chlorobenzoate
-
-
?
