6.2.1.33: 4-chlorobenzoate-CoA ligase
This is an abbreviated version!
For detailed information about 4-chlorobenzoate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.33
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6.2.1.33
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dehalogenase
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4-hydroxybenzoate
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thioesterase
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amp
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half-reaction
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thioester-forming
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adenylate-forming
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thioesterification
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acyl-adenylate
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4-hydroxybenzoyl-coa
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homotetramer
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dehalogenation
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4-cba-coa
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single-turnover
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pantetheine
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aryl-coa
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alcaligenes
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diester
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chlorinate
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mgatp
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poised
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arthrobacter
- 6.2.1.33
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dehalogenase
- 4-hydroxybenzoate
-
thioesterase
- amp
-
half-reaction
-
thioester-forming
-
adenylate-forming
-
thioesterification
-
acyl-adenylate
- 4-hydroxybenzoyl-coa
-
homotetramer
-
dehalogenation
-
4-cba-coa
-
single-turnover
- pantetheine
- aryl-coa
- alcaligenes
-
diester
-
chlorinate
- mgatp
-
poised
-
arthrobacter
Reaction
Synonyms
4-CB:CoA ligase, 4-CBA:CoA ligase, 4-chlorobenzoate:CoA ligase, 4-Chlorobenzoate:coenzyme A ligase, 4-Chlorobenzoyl-CoA ligase, 4-Chlorobenzoyl-coenzyme A ligase, 4-Halobenzoate-coenzyme A ligase, CBAL, CBL, chlorobenzoate:CoA ligase, Synthetase, 4-chlorobenzoyl coenzyme A
ECTree
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Reaction
Reaction on EC 6.2.1.33 - 4-chlorobenzoate-CoA ligase
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two-step reaction consisting of the adenylation of 4-chlorobenzoate with adenosine 5'-triphosphate followed by acyl transfer from 4-chlorobenzoyl adenosine 5'-monophosphate diester
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4-Chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate
4-chlorobenzoyl-adenosine 5'-phosphate diester is formed by the first partial reaction
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4-Chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate
kinetic reaction mechanism, overview
4-Chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate
the enzyme alternates between two conformations during catalysis of the two half-reactions, structure-function analysis, domain alternation strategy, overview
4-Chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate
two-step reaction consisting of the adenylation of 4-chlorobenzoate with adenosine 5'-triphosphate followed by acyl transfer from 4-chlorobenzoyl adenosine 5'-monophosphate diester
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4-Chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate
4-chlorobenzoyl-adenosine 5'-phosphate diester is formed by the first partial reaction
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