6.2.1.25: benzoate-CoA ligase
This is an abbreviated version!
For detailed information about benzoate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.25
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6.2.1.25
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denitrifying
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benzoyl-coenzyme
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thauera
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palustris
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aromatica
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n-acyltransferase
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benzoylglycine
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benzoate-induced
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2-aminobenzoate
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azoarcus
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3-hydroxybenzoyl-coa
- 6.2.1.25
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denitrifying
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benzoyl-coenzyme
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thauera
- palustris
- aromatica
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n-acyltransferase
- benzoylglycine
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benzoate-induced
- 2-aminobenzoate
- azoarcus
- 3-hydroxybenzoyl-coa
Reaction
Synonyms
AMP-forming BCL, AMP-forming benzoate-CoA ligase, BadA, BamY, Bcl, bclA, BCLM, benzoate CoA ligase, Benzoate coenzyme A ligase, benzoate-CoA ligase, Benzoate-CoA ligase (AMP-forming), Benzoyl coenzyme A synthetase, Benzoyl-CoA ligase, Benzoyl-CoA synthetase, BzdA enzyme, Synthetase, benzoyl coenzyme A, XabE
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Natural Substrates Products on EC 6.2.1.25 - benzoate-CoA ligase
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REACTION DIAGRAM
ATP + 2-fluorobenzoate + CoA
AMP + diphosphate + 2-fluorobenzoyl-CoA
activation of 2-fluorobenzoate by promiscuous AMP-forming benzoate-CoA ligase
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additional information
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benzoate degradation in Azoarcus sp. strain CIB is subject to carbon catabolic repression by some organic acids, indicating the existence of a physiological control that connects the expression of the bzd genes to the metabolic status of the cell
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enzyme is involved in anaerobic degradation of benzoate
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ATP + benzoate + CoA
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activation of benzoate to benzoyl-CoA, a more polar and nondiffusable molecule, decreases the concentration of benzoate in the cell, creating a gradient that favored the uptake of benzoate from the environment
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ATP + benzoate + CoA
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first step of anaerobic benzoate degradation
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AMP + diphosphate + benzoyl-CoA
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ATP + benzoate + CoA
AMP + diphosphate + benzoyl-CoA
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the enzyme catalyzes the initial step of benzoate metabolism
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ATP + benzoate + CoA
AMP + diphosphate + benzoyl-CoA
Geobacter metallireducens GS-15 / ATCC 53774 / DSM 7210
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ATP + benzoate + CoA
AMP + diphosphate + benzoyl-CoA
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