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6.2.1.20: long-chain-fatty-acid-[acyl-carrier-protein] ligase

This is an abbreviated version!
For detailed information about long-chain-fatty-acid-[acyl-carrier-protein] ligase, go to the full flat file.

Word Map on EC 6.2.1.20

Reaction

ATP
+
a long-chain fatty acid
+
an [acyl-carrier protein]
=
AMP
+
diphosphate
+
a long-chain acyl-[acyl-carrier protein]

Synonyms

AAE15, AAS, AasC, AasS, ACP synthase, AcpS, ACSL, acyl carrier protein synthase, acyl-ACP synthase, Acyl-ACP synthetase, Acyl-acyl carrier protein synthetase, Acyl-CoA ligase, Acyl-CoA synthetase, Acyl-[acyl carrier protein] synthetase, Acyl-[acyl-carrier-protein]synthetase, At4g14070, CT776, CTO_0846, LipA, PfACP, slr1609, Stearoyl-ACP synthetase, Synthetase, acyl-[acyl carrier protein]

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.20 long-chain-fatty-acid-[acyl-carrier-protein] ligase

Substrates Products

Substrates Products on EC 6.2.1.20 - long-chain-fatty-acid-[acyl-carrier-protein] ligase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + a long-chain fatty acid + an [acyl-carrier protein]
AMP + diphosphate + a long-chain acyl-[acyl-carrier protein]
show the reaction diagram
ATP + a long-chain fatty acid + LipD
AMP + diphosphate + a long-chain acyl-LipD
show the reaction diagram
ATP + an acid + [acyl-carrier protein]
?
show the reaction diagram
-
enzyme functions in the incorporation of fatty acids into phospholipid
-
-
?
ATP + an acid + [acyl-carrier protein]
AMP + diphosphate + acyl-[acyl-carrier protein]
show the reaction diagram
ATP + cis-vaccenic acid + [acyl-carrier protein]
AMP + diphosphate + cis-vaccenoyl-[acyl-carrier protein]
show the reaction diagram
-
-
-
-
?
ATP + decanoate + an [acyl-carrier protein]
AMP + diphosphate + long-chain decanoyl-[acyl-carrier protein]
show the reaction diagram
-
-
-
?
ATP + decanoic acid + [acyl-carrier protein]
AMP + diphosphate + decanoyl-[acyl-carrier protein]
show the reaction diagram
ATP + hexadecanoate + an [acyl-carrier protein]
AMP + diphosphate + hexadecanoyl-[acyl-carrier protein]
show the reaction diagram
low activity
-
-
?
ATP + hexanoic acid + [acyl-carrier protein]
AMP + diphosphate + hexanoyl-[acyl-carrier protein]
show the reaction diagram
ATP + laurate + an [acyl-carrier protein]
AMP + diphosphate + lauroyl-[acyl-carrier protein]
show the reaction diagram
-
-
-
?
ATP + lauric acid + [acyl-carrier protein]
AMP + diphosphate + lauroyl-[acyl-carrier protein]
show the reaction diagram
ATP + linoleic acid + [acyl-carrier protein]
AMP + diphosphate + linoleoyl-[acyl-carrier protein]
show the reaction diagram
ATP + myristate + an [acyl-carrier protein]
AMP + diphosphate + myristoyl-[acyl-carrier protein]
show the reaction diagram
-
-
-
?
ATP + myristic acid + [acyl-carrier protein]
AMP + diphosphate + myristoyl-[acyl-carrier protein]
show the reaction diagram
ATP + octanoate + an [acyl-carrier protein]
AMP + diphosphate + octanoyl-[acyl-carrier protein]
show the reaction diagram
low activity
-
-
?
ATP + octanoate + [AcpP1]
AMP + diphosphate + octanoyl-[AcpP1]
show the reaction diagram
recombinant holo-AcpP1 from Pseudomonas aeruginosa
-
-
?
ATP + octanoate + [AcpP2]
AMP + diphosphate + octanoyl-[AcpP2]
show the reaction diagram
recombinant holo-AcpP2 from Pseudomonas aeruginosa
-
-
?
ATP + octanoate + [AcpP3]
AMP + diphosphate + octanoyl-[AcpP3]
show the reaction diagram
recombinant holo-AcpP3 from Pseudomonas aeruginosa
-
-
?
ATP + octanoate + [acyl-carrier protein]
AMP + diphosphate + octanoyl-[acyl-carrier protein]
show the reaction diagram
ATP + octanoic acid + [acyl-carrier protein]
AMP + diphosphate + octanoyl-[acyl-carrier protein]
show the reaction diagram
ATP + oleate + an [acyl-carrier protein]
AMP + diphosphate + oleoyl-[acyl-carrier protein]
show the reaction diagram
ATP + oleic acid + [acyl-carrier protein]
AMP + diphosphate + oleoyl-[acyl-carrier protein]
show the reaction diagram
ATP + palmitate + an [acyl-carrier protein]
AMP + diphosphate + palmitoyl-[acyl-carrier protein]
show the reaction diagram
ATP + palmitic acid + [acyl-carrier protein]
AMP + diphosphate + palmitoyl-[acyl-carrier protein]
show the reaction diagram
ATP + palmitoleic acid + [acyl-carrier protein]
AMP + diphosphate + palmitoleoyl-[acyl-carrier protein]
show the reaction diagram
ATP + saturated fatty acids + an [acyl-carrier protein]
?
show the reaction diagram
-
-
-
-
?
ATP + stearic acid + [acyl-carrier protein]
AMP + diphosphate + stearoyl-[acyl-carrier protein]
show the reaction diagram
ATP + tetradecanoate + [acyl-carrier protein]
AMP + diphosphate + tetradecanoyl-[acyl-carrier protein]
show the reaction diagram
ATP + unsaturated fatty acids + an [acyl-carrier protein]
?
show the reaction diagram
-
-
-
-
?
dATP + a fatty acid + [acyl-carrier protein]
dAMP + diphosphate + fatty acid-[acyl-carrier protein]
show the reaction diagram
-
25% of the activity relative to ATP
-
-
?
additional information
?
-