6.2.1.16: acetoacetate-CoA ligase
This is an abbreviated version!
For detailed information about acetoacetate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.16
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6.2.1.16
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ketone
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cholesterol
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lipogenesis
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body-utilizing
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lipogenic
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thiolase
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hmg-coa
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3-hydroxybutyrate
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coa-transferase
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cholestyramine
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zoogloea
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ramigera
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srebp-2
- 6.2.1.16
- ketone
- cholesterol
-
lipogenesis
-
body-utilizing
-
lipogenic
-
thiolase
- hmg-coa
- 3-hydroxybutyrate
-
coa-transferase
- cholestyramine
-
zoogloea
- ramigera
- srebp-2
Reaction
Synonyms
Aacl, AACS, Acetoacetate--CoA ligase, Acetoacetyl CoA synthetase, Acetoacetyl-CoA ligase, Acetoacetyl-CoA synthase, Acetoacetyl-CoA synthetase, Acetoacetyl-coenzyme A synthetase, acsA1, SlAacS, Synthetase, acetoacetyl coenzyme A
ECTree
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Expression
Expression on EC 6.2.1.16 - acetoacetate-CoA ligase
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peroxisome-proliferator-activated receptor gamm, PPARgamma, induces AACS and adipogenesis. A PPAR-responsive element, PPRE-independent mechanism might be involved in PPARgamma-mediated AACS gene expression. PPARgamma-dependent activation of the human AACS gene is mediated by the GC boxes
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specificity protein 1 (Sp1) binds to the Sp1 binding site on the promoter region of AACS. Overexpression of Sp1 increases AACS mRNA levels
specificity protein 1 (Sp1) regulates gene expression of AACS in Neuro-2a cells, investigation of promoter activity of AACS, overview
the human AACS promoter is a PPARgamma target gene. Nuclear receptor PPARgamma is recruited to the AACS promoter by direct interaction with Sp1
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treatment of hepatocytes with U18666A results in the upregulation of AACS gene expression
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treatment of hepatocytes with U18666A results in the upregulation of AACS gene expression
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