6.2.1.13: acetate-CoA ligase (ADP-forming)

This is an abbreviated version!
For detailed information about acetate-CoA ligase (ADP-forming), go to the full flat file.

Reaction

Synonyms

ACD, acetate:CoA ligase [ADP-forming], acetate:coenzyme A ligase (ADP-forming), Acetyl-CoA synthetase, Acetyl-CoA synthetase (ADP-forming), acetyl-coenzyme A synthetase, acetyl-coenzyme A synthetase (ADP-forming), ACS, ACS III, ACS1, ACS2, ADP acetyl-coenzyme A synthetase, ADP-ACS, ADP-forming acetyl-CoA synthetase, ADP-forming acetyl-CoA synthetase isoenzyme I, ADP-forming acetyl-coenzyme A synthetase, ADP-forming acyl coenzyme A synthetase, ADP-forming acyl-CoA synthetase, EhACD, PF1540, PF1787, Synthetase, acetyl coenzyme A (adenosine diphosphate-forming), TK0944/TK0943 protein

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.13 acetate-CoA ligase (ADP-forming)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2060	AA Sequence
1	CAS Registry Number
12	Cloned(Commentary)
14	Cofactor
1	Crystallization (Commentary)
2	Expression
9	General Information
4	General Stability
3	IC50 Value
11	Inhibitors
86	kcat/KM [mM/s]
178	KM Value [mM]
5	Localization
27	Metals/Ions
28	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
42	Organism
1	Oxidation Stability
16	Pathway
14	pH Optimum
7	pH Range
1	pI Value
1	Posttranslational Modification
27	Protein Variants
20	Purification (Commentary)
4	Reaction
1	Reaction Type
33	Reference
2	Renatured (Commentary)
10	Source Tissue
12	Specific Activity [micromol/min/mg]
3	Storage Stability
135	Substrates and Products (Substrate)
19	Subunits
49	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
5	Temperature Range [°C]
7	Temperature Stability [°C]
100	Turnover Number [1/s]

pH Range

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

pH Range on EC 6.2.1.13 - acetate-CoA ligase (ADP-forming)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to pH Range Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5.5 - 7.5

Pyrobaculum aerophilum

-

pH 5.5: about 40% of maximal activity, pH 7.5: about 20% of maximal activity

660834

6 - 11

Pyrococcus furiosus

-

6: about 60% of maximal activity, 11: about 40% of maximal activity, isoenzyme ACS I

626

6 - 7

Entamoeba histolytica

Q9NAT4

at pH 6.0-7.0, the recombinant enzyme shows 15–60% of the maximum activity

744414

6 - 8

Pyrococcus furiosus

-

about 50% of maximal activity at pH 6 and 8

625

6.5 - 8.5

Haloarcula marismortui

-

pH 6.5: about 60% of maximal activity, pH 8.5: about 60% of maximal activity

660834

7 - 11

Pyrococcus furiosus

-

7: about 60% of maximal activity, 11: about 65% of maximal activity, isoenzyme ACS II

626

7.3 - 7.8

Chloroflexus aurantiacus

-

the pH optimum is at pH 7.5, with remaining activities of about 40% at pH 7.3 and 59% at pH 7.8

727557