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6.2.1.13: acetate-CoA ligase (ADP-forming)

This is an abbreviated version!
For detailed information about acetate-CoA ligase (ADP-forming), go to the full flat file.

Word Map on EC 6.2.1.13

Reaction

ATP
+
acetate
 +
CoA
=
ADP
 +
phosphate
 +
acetyl-CoA

Synonyms

ACD, acetate:CoA ligase [ADP-forming], acetate:coenzyme A ligase (ADP-forming), Acetyl-CoA synthetase, Acetyl-CoA synthetase (ADP-forming), acetyl-coenzyme A synthetase, acetyl-coenzyme A synthetase (ADP-forming), ACS, ACS III, ACS1, ACS2, ADP acetyl-coenzyme A synthetase, ADP-ACS, ADP-forming acetyl-CoA synthetase, ADP-forming acetyl-CoA synthetase isoenzyme I, ADP-forming acetyl-coenzyme A synthetase, ADP-forming acyl coenzyme A synthetase, ADP-forming acyl-CoA synthetase, EhACD, PF1540, PF1787, Synthetase, acetyl coenzyme A (adenosine diphosphate-forming), TK0944/TK0943 protein

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.13 acetate-CoA ligase (ADP-forming)

Temperature Range

Temperature Range on EC 6.2.1.13 - acetate-CoA ligase (ADP-forming)

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TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20 - 40
-
20°C: about 75% of maximal activity, 40°C: about 45% of maximal activity, isoenzyme ACS1
25
-
isoenzymes ACS I and ACS II are inactive at
25 - 55
-
25°C: about 45% of maximal activity, 55°C: about 40% of maximal activity, isoenzyme ACS2
30 - 50
-
30°C: about 50% of maximal activity, 50°C: about 80% of maximal activity
37
the enzyme exhibits 70% activity at 37°C