6.1.1.4: leucine-tRNA ligase
This is an abbreviated version!
For detailed information about leucine-tRNA ligase, go to the full flat file.
Word Map on EC 6.1.1.4
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6.1.1.4
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aminoacyl-trna
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synthetases
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aminoacylation
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fidelity
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leucylation
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aarss
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mischarged
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post-transfer
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norvaline
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perrault
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anticodon
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aeolicus
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isoacceptors
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misactivated
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aquifex
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ilers
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noncognate
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valrs
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benzoxaborole
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isoleucyl-trna
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misaminoacylated
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hsd17b4
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kmsks
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metrs
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pour
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trnaser
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clinique
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trnaleuuur
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valyl-trna
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isoleucyl
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trna-dependent
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pre-transfer
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drug development
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medicine
- 6.1.1.4
- aminoacyl-trna
- synthetases
- aminoacylation
-
fidelity
-
leucylation
-
aarss
-
mischarged
-
post-transfer
- norvaline
-
perrault
-
anticodon
- aeolicus
-
isoacceptors
-
misactivated
-
aquifex
- ilers
-
noncognate
- valrs
-
benzoxaborole
-
isoleucyl-trna
-
misaminoacylated
- hsd17b4
-
kmsks
- metrs
-
pour
- trnaser
-
clinique
- trnaleuuur
- valyl-trna
-
isoleucyl
-
trna-dependent
-
pre-transfer
- drug development
- medicine
Reaction
Synonyms
AaLeuRS, alphabeta-LeuRS, b0642, cytoplasmic LeuRS, EcLeuRS, GlLeuRS, HcleuRS, hs mt LeuRS, JW0637, LARS, LARS1, LARS2, Leucine translase, Leucine--tRNA ligase, Leucyl-transfer ribonucleate synthetase, Leucyl-transfer ribonucleic acid synthetase, Leucyl-transfer RNA synthetase, leucyl-tRNA ligase, leucyl-tRNA syntethase, Leucyl-tRNA synthetase, leucyl-tRNA synthetase 1, leucyl—tRNA synthetase, LeuRS, LeuRS1, LeuRS2, LeuRSTT, leuS, LRS, MmLeuRS, More, mt leucyl-tRNA synthetase, mt-LeuRS, mtLeuRS, PhLeuRS, Synthetase, leucyl-transfer ribonucleate, ycLeuRS
ECTree
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Specific Activity
Specific Activity on EC 6.1.1.4 - leucine-tRNA ligase
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0.024
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mutant A293D, in crude enzyme extract of Escherichia coli strain TG1
0.047
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purified recombinant wild-type enzyme, with substrate tRNALeu from Escherichia coli
0.14
0.235
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purified recombinant wild-type enzyme, with substrate tRNALeu from Aquifex aeolicus
0.28
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wild-type enzyme, in crude enzyme extract of Escherichia coli strain TG1
0.29
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mutant T252E/M328K, in crude enzyme extract of Escherichia coli strain TG1
1.3
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purified recombinant wild-type enzyme, with substrate tRNALeu from Aquifex aeolicus
1.5
additional information
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mutants A293I, A293G, and A293Y, in crude enzyme extract of Escherichia coli strain TG1
1.5
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purified recombinant wild-type enzyme, with substrate tRNALeu from Escherichia coli
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activiy of several enzyme mutants and mixed mutants, containing subparts of the Escherichia coli enzyme
additional information
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mischarging and post-transfer editing activities, overview
additional information
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activiy of several enzyme mutants and mixed mutants, containing subparts of the Escherichia coli enzyme
additional information
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aminoacid activation activities of wild-type and mutant enzymes
additional information
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hydrolytic post-transfer editing activity of wild-type and D345A mutant LeuRS CP1 domains, activities of truncation mutants, overview
additional information
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activity and specificity of several truncation and deletion mutants, overview