6.1.1.22: asparagine-tRNA ligase
This is an abbreviated version!
For detailed information about asparagine-tRNA ligase, go to the full flat file.
Word Map on EC 6.1.1.22
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6.1.1.22
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aminoacyl-trna
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asnrs
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aspartyl-trna
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malayi
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brugia
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aminoacylation
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amidotransferase
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asparaginylation
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asp-trnaasn
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glutaminyl-trna
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gatcabs
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filariasis
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transamidation
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nondiscriminating
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glu-trnagln
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mischarged
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misacylated
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asn-trna
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nd-asprs
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ammonia-dependent
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anti-ks
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lysyl-trna
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trnaasp
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histidyl-trna
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medicine
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drug development
- 6.1.1.22
- aminoacyl-trna
- asnrs
- aspartyl-trna
- malayi
- brugia
- aminoacylation
-
amidotransferase
-
asparaginylation
- asp-trnaasn
- glutaminyl-trna
- gatcabs
- filariasis
-
transamidation
-
nondiscriminating
- glu-trnagln
-
mischarged
-
misacylated
-
asn-trna
- nd-asprs
-
ammonia-dependent
-
anti-ks
- lysyl-trna
- trnaasp
-
histidyl-trna
- medicine
- drug development
Reaction
Synonyms
AS-AR, AsnRS, Asparagine synthetase A, Asparagine translase, asparagine tRNA synthetase, Asparagine--tRNA ligase, Asparaginyl transfer ribonucleic acid synthetase, Asparaginyl transfer RNA synthetase, asparaginyl tRNA synthetase, Asparaginyl-transfer ribonucleate synthetase, asparaginyl-transfer RNA synthetase, Asparaginyl-tRNA synthetase, Asparagyl-transfer RNA synthetase, class IIb asparaginyl-tRNA synthetase, More, NARS, NARS2, NRS, Potentially protective 63 kDa antigen, PYRAB02460, Synthetase, asparaginyl-transfer ribonucleate
ECTree
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Molecular Weight
Molecular Weight on EC 6.1.1.22 - asparagine-tRNA ligase
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120000
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calculation from gel filtration and sedimentation velocity
127000
152000
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wild-type and mutant enzyme, sucrose density gradient centrifugation
175000
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cytoplasmic enzyme, dissociated activity arises from high molecular weight aminoacyl-tRNA synthetase complex, gel filtration
189000
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mitochondrial enzyme, dissociated activity arises from high molecular weight aminoacyl-tRNA synthetase complex, gel filtration
50000
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x * 50875, calculation from nucleotide sequence, x * 50000, SDS-PAGE
50875
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x * 50875, calculation from nucleotide sequence, x * 50000, SDS-PAGE
51000
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2 * 51000, sedimentation equilibrium measurement under denaturing conditions
additional information
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existence of high molecular weight aminoacyl-tRNA synthetase complexes within the mitochondria and the cytoplasm
additional information
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MW 35000 component with transfer activity and a MW 80000-90000 component that requires the addition of an activator for transfer activity, gel filtration
additional information
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high similarity with other bacterial asparaginyl-tRNA synthetase sequences (30-55% identity)