6.1.1.21: histidine-tRNA ligase
This is an abbreviated version!
For detailed information about histidine-tRNA ligase, go to the full flat file.
Word Map on EC 6.1.1.21
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6.1.1.21
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synthetases
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aminoacylation
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aminoacyl-trna
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autoantibody
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histidylation
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myositis
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anti-jo-1
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polymyositis
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anticodon
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dermatomyositis
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aarss
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perrault
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hiss
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histidinol
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anti-synthetase
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guanylyltransferase
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hsd17b4
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myositis-specific
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c10orf2
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thrrs
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threonyl-trna
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trna-like
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acid-starved
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seryl-trna
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analysis
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medicine
- 6.1.1.21
- synthetases
- aminoacylation
- aminoacyl-trna
- autoantibody
-
histidylation
- myositis
-
anti-jo-1
- polymyositis
-
anticodon
- dermatomyositis
-
aarss
-
perrault
- hiss
- histidinol
-
anti-synthetase
-
guanylyltransferase
- hsd17b4
-
myositis-specific
- c10orf2
- thrrs
- threonyl-trna
-
trna-like
-
acid-starved
- seryl-trna
- analysis
- medicine
Reaction
Synonyms
antihistidyl-tRNA synthetase, class II histidyl-tRNA synthetase, HARS, HARS1, HARS2, HisRS, HisRS-1, HisRS-2, Histidine translase, Histidine--tRNA ligase, Histidine--tRNA ligase homolog, histidine-tRNA ligase, histidine-tRNA ligase homolog, histidyl tRNA synthetase, Histidyl-transfer ribonucleate synthetase, histidyl-transfer RNA synthetase, Histidyl-tRNA synthetase, HRS, HTS1, Jo-1, Jo-1 antigen, mitochondrial histidyl tRNA synthetase, Synthetase, histidyl-transfer ribonucleate
ECTree
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KM Value
KM Value on EC 6.1.1.21 - histidine-tRNA ligase
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0.017
His
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mutant enzyme form V-HisRS, mutant enzyme form V-His-RS-R259K, aminoacylation
0.000006
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unfractionated substrate from rabbit liver or rabbit reticulocyte tRNAHisI
0.00325
tRNAHis
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wild-type Caulobacter crescentus tRNAHis, pH 7.5, 30°C
additional information
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kinetics and substrate specificity
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additional information
additional information
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kinetics with diverse tRNAHIs variants, overview
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additional information
additional information
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Michaelis-Menten kinetics for the wild-type enzyme and recombinant HisRS active site fragments, HisRS1-HisRS4, overview
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