6.1.1.2: tryptophan-tRNA ligase

This is an abbreviated version!
For detailed information about tryptophan-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.2

6.1.1.2

synthetases

aminoacyl-trna

aminoacylation

pancreas

beef

anticodon

stearothermophilus

tyrrs

tyrosyl-trna

indoleamine

angiostatic

kmsks

ido

tryptamine

tryptophan-dependent

aarss

ap4a

glutaminyl-trna

hisrs

anticodon-binding

glnrs

medicine

synthesis

biotechnology

Reaction

Synonyms

(Mt)TrpRS, BsTRpRS, drTrpRS II, EcTrpRS, hTrpRS, hWRS, IFP53, mini tryptophanyl-tRNA synthetase, mini-TrpRS, More, Synthetase, tryptophanyl-transfer ribonucleate, T2-TrpRS, Trp-RS, TrpRS, TrpRS II, TrpRS Urzyme, TrpRS1, TrpRS2, Tryptophan translase, Tryptophan--tRNA ligase, Tryptophanyl ribonucleic synthetase, tryptophanyl tRNA synthase, tryptophanyl tRNA synthetase, Tryptophanyl-transfer ribonucleate synthetase, Tryptophanyl-transfer ribonucleic acid synthetase, Tryptophanyl-transfer ribonucleic synthetase, Tryptophanyl-transfer RNA synthetase, Tryptophanyl-tRNA synthase, Tryptophanyl-tRNA synthetase, tryptophanyl-tRNA synthetase II, tryptophanyl-tRNA synthetase1, tryptophanyl-tRNA synthetase2, trytophanyl-tRNA synthetase, tyrosyl tRNA synthetase, WARS, WARS2, WRS

ECTree

6 Ligases

6.1 Forming carbon-oxygen bonds

6.1.1 Ligases forming aminoacyl-tRNA and related compounds

6.1.1.2 tryptophan-tRNA ligase

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Results	in table
18	Activating Compound
56670	AA Sequence
8	Application
1	CAS Registry Number
47	Cloned(Commentary)
56	Cofactor
23	Crystallization (Commentary)
218	Disease/ Diagnostics
2	Expression
31	General Information
5	General Stability
7	IC50 Value
68	Inhibitors
2	kcat/KM [mM/s]
2	Ki Value [mM]
113	KM Value [mM]
27	Localization
38	Metals/Ions
18	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
174	Organism
4	Pathway
155	PDB ID
30	pH Optimum
3	pH Range
4	Posttranslational Modification
119	Protein Variants
34	Purification (Commentary)
7	Reaction
46	Reaction Type
117	Reference
2	Renatured (Commentary)
76	Source Tissue
6	Specific Activity [micromol/min/mg]
6	Storage Stability
207	Substrates and Products (Substrate)
22	Subunits
184	Synonyms
1	Systematic Name
29	Temperature Optimum [°C]
2	Temperature Stability [°C]
92	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 6.1.1.2 - tryptophan-tRNA ligase

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108000

Bos taurus

gel filtration, enzyme form TRS108, equilibrium sedimentation

294

120000

Bos taurus

gel filtration

299

140000

Plasmodium falciparum

Q8IDW3

gel filtration

728611

200000

Lupinus luteus

gel filtration

35000

Homo sapiens

Q9UGM6

x * 35000, recombinant His-tagged enzyme, expressed in insect cells, SDS-PAGE

651999

37000

Lupinus luteus

possibly 4 * 37000, SDS-PAGE

49000

Homo sapiens

P23381

transcript variant of WARS, determined by SDS-PAGE and Western blot analysis

705840

53000

3 entries

54000

Bos taurus

2 * 54000, enzyme form TRS108, SDS-PAGE

294

60000

Bos taurus

2 * 60000, SDS-PAGE

299

70000 - 83000

Bos taurus

enzyme form TRS82, gel filtration, equilibrium sedimentation, gel electrophoresis

294

73000

Plasmodium falciparum

Q8IDW3

2 * 73000, SDS-PAGE

728611

88000

Bos taurus

enzyme form TRS88, gel electrophoresis

294

additional information

3 entries