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6.1.1.18: glutamine-tRNA ligase

This is an abbreviated version!
For detailed information about glutamine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.18

Reaction

ATP
+
L-glutamine
+
tRNAGln
=
AMP
+
diphosphate
+
L-glutaminyl-tRNAGln

Synonyms

class I glutaminyl-tRNA synthetase, cytosolic glutaminyl-tRNA synthetase, Gln-RS, Gln4, GlnRS, Glutamine translase, Glutamine--tRNA ligase, Glutamine-tRNA synthetase, glutaminyl tRNA synthetase, Glutaminyl-transfer ribonucleate synthetase, Glutaminyl-transfer RNA synthetase, Glutaminyl-tRNA synthetase, glutaminyltRNA synthetase, glutamyl/glutaminyl-tRNA synthetase, QARS, QRS, Synthetase, glutaminyl-transfer ribonucleate, Vegetative specific protein H4

ECTree

     6 Ligases
         6.1 Forming carbon-oxygen bonds
             6.1.1 Ligases forming aminoacyl-tRNA and related compounds
                6.1.1.18 glutamine-tRNA ligase

Specific Activity

Specific Activity on EC 6.1.1.18 - glutamine-tRNA ligase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00024 - 0.00033
recombinant mutant Y57H/R515W enzyme in crude cell extract, pH 7.5, 37°C
0.00028
recombinant mutant G45V/R403W enzyme in crude cell extract, pH 7.5, 37°C
0.00041
recombinant mutant G45V enzyme in crude cell extract, pH 7.5, 37°C
0.00051
recombinant mutant R515W enzyme in crude cell extract, pH 7.5, 37°C
0.00058
recombinant mutant Y57H enzyme in crude cell extract, pH 7.5, 37°C
0.00079 - 0.00083
recombinant wild-type enzyme in crude cell extract, pH 7.5, 37°C
0.1074
-
-
additional information