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6.1.1.11: serine-tRNA ligase

This is an abbreviated version!
For detailed information about serine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.11

Reaction

ATP
+
L-serine
+
tRNASer
=
AMP
+
diphosphate
+
L-seryl-tRNASer

Synonyms

62 kDa RNA-binding protein, bacterial SerRS, bacterial type seryl-tRNA synthetase, bacterial-type SerRS, bMbSerRS, methanogenic SerRS, methanogenic type seryl-tRNA synthetase, methanogenic-type SerRS, methanogenic-type SerRSs, methanogenic-type seryl-tRNA synthetase, mMbSerRS, mSerRS, mtSerRS, SARS, SCSerS, Serine transfer RNA synthetase, Serine translase, Serine--tRNA ligase, SerRS, SerRS1, SerRS2, SerRSmt, serS, SERSEC, seryl tRNA synthetase, Seryl-transfer ribonucleate synthetase, Seryl-transfer ribonucleic acid synthetase, Seryl-transfer RNA synthetase, Seryl-tRNA synthetase, seryl-tRNA synthetase 1, seryl-tRNA synthetase 2, seryl-tRNA-synthetase, SerZMo, STS, subclass IIa dimeric SerRS, SvsR, Synthetase, seryl-transfer ribonucleate, tRNASer/seryl-tRNA synthetase, ttSerRS, TT_C0520, VlmL, ZmSerS

ECTree

     6 Ligases
         6.1 Forming carbon-oxygen bonds
             6.1.1 Ligases forming aminoacyl-tRNA and related compounds
                6.1.1.11 serine-tRNA ligase

KCat KM Value

KCat KM Value on EC 6.1.1.11 - serine-tRNA ligase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.04
DL-Serine hydroxamate
-
in 50 mM HEPES pH 7.0, 25 mM KCl, 20 mM MgCl2, temperature not specified in the publication
0.0027
L-cysteine
-
in 50 mM HEPES pH 7.0, 25 mM KCl, 20 mM MgCl2, temperature not specified in the publication
0.016 - 13.9
L-serine
0.006
L-threonine
-
in 50 mM HEPES pH 7.0, 25 mM KCl, 20 mM MgCl2, temperature not specified in the publication
298
tRNASec
at pH 7.6, temperature not specified in the publication
-
1275 - 1900
tRNASer
180
tRNASer (Escherichia coli)
-
at pH 7.5 and 30°C
-
140
tRNASer (Saccharomyces cerevisiae)
-
at pH 7.5 and 30°C
-