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6.1.1.1: tyrosine-tRNA ligase

This is an abbreviated version!
For detailed information about tyrosine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.1

Reaction

ATP
+
L-tyrosine
+
tRNATyr
=
AMP
+
diphosphate
+
L-tyrosyl-tRNATyr

Synonyms

CHOTyrRS, class I tyrosyl-tRNA synthetase, CYT-18, CYT-18 protein, dTyRS, hTyrRS, LdTyrRS, LMJF_14_1370, mini-tyrosyl-tRNA synthetase, mini-TyrRS, mitochondrial tyrosyl-tRNA synthetase, MjYRS, mt-TyrRS, mtTyrRS, NpAla TyrRS, p-BrPhe TyrRS, tRNATyr/tyrosyl-tRNA synthetase, Tyrosine translase, Tyrosine tRNA synthetase, Tyrosine--tRNA ligase, Tyrosine-transfer ribonucleate synthetase, Tyrosine-transfer RNA ligase, tyrosyl aminoacyl-tRNA synthetase, tyrosyl synthetase, tyrosyl tRNA synthetase, Tyrosyl--tRNA ligase, Tyrosyl-transfer ribonucleate synthetase, Tyrosyl-transfer ribonucleic acid synthetase, Tyrosyl-transfer RNA synthetase, Tyrosyl-tRNA ligase, Tyrosyl-tRNA synthetase, tyrosyl—tRNA synthetase, TyrRS, TyrRSs, TyrRZ, tyrS, TYS1, YARS, YRS, YTS

ECTree

     6 Ligases
         6.1 Forming carbon-oxygen bonds
             6.1.1 Ligases forming aminoacyl-tRNA and related compounds
                6.1.1.1 tyrosine-tRNA ligase

Expression

Expression on EC 6.1.1.1 - tyrosine-tRNA ligase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
high glucose significantly decreases mRNA expression of tyrosyl-tRNA synthetase
-
lysine acetylation can be a possible mechanism for modulating aminoacyl-tRNA synthetases enzyme activities, thus affecting translation
treatment of silkworms with phoxim, an inhibitor of silk protein synthesis, but not TiO2 NP, an enhancer of silk protein synthesis, significantly reduce the transcription levels of aminoacyl-tRNA synthetases and content of free amino acids in posterior silk gland, therefore affecting silk protein synthesis, which may be the mechanism of phoxim-silking disorders. Low concentration of TiO2 NPs shows no effect on the transcription of aminoacyl-tRNA synthetases and content of free amino acids, suggesting that TiO2 NPs promotes silk protein synthesis possibly by increasing the activity of fibroin synthase in silkworm