5.5.1.4: inositol-3-phosphate synthase

This is an abbreviated version!
For detailed information about inositol-3-phosphate synthase, go to the full flat file.

Reaction

Synonyms

1D-myo-inositol 3-phosphate synthase, 1L-myo-Inositol-1-phosphate synthase, AtMIPS1, AtMIPS2-1, AtMIPS3, CaMIPS1, CaMIPS2, D-Glucose 6-phosphate cycloaldolase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cyclase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase, D-Glucose 6-phosphate-L-myo-inositol 1-phosphate cyclase, D-Glucose-6-phosphate,L-myo-inositol-1-phosphate cycloaldolase, D-myo-inositol-3-phosphate synthase, Glucocycloaldolase, Glucose 6-phosphate cyclase, Glucose-6-phosphate inositol monophosphate cycloaldolase, INO-1, INO-2, INO1, Ino1p, iNOS, Inositol 1-phosphate synthase, Inositol 1-phosphate synthetase, inositol 3-phosphate synthase, inositol phosphate synthase, inositol-1-phosphate synthase, inositol-3-phosphate synthase, INPS, INPS1, INS (3) P1 synthase, IP synthase, IPS, L-myo-inositol 1-phosphate synthase, L-myo-Inositol 1-phosphate synthetase, L-myo-Inositol-1-phosphate synthase, MI-1-P synthase, MIP synthase, MIPS, MIPS1, MIPS2, myo-D-inositol 3-phosphate synthase, myo-inositol 1-phosphate synthase, myo-inositol 3-phosphate synthase, myo-inositol phosphate synthase, myo-Inositol-1-P synthase, Myo-inositol-1-phosphate synthase, myo-inositol-3-phosphate synthase, OsMIPS1, OsMIPS1-1, OsMIPS1-2, OsMIPS1-3, OsMIPS2, PcINO1, PINO1 protein, PIP synthase, PIPS, RINO1 protein, SaINO1, sll1981, Synthase, myo-inositol 1-phosphate, TaMIPS1, TaMIPS2, tbINO, yMIP synthase, [Ins(3)P1] synthase

ECTree

     5 Isomerases

         5.5 Intramolecular lyases

             5.5.1 Intramolecular lyases (only sub-subclass identified to date)

                5.5.1.4 inositol-3-phosphate synthase

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Results	in table
18	Activating Compound
6124	AA Sequence
7	Application
1	CAS Registry Number
39	Cloned(Commentary)
101	Cofactor
8	Crystallization (Commentary)
79	Disease/ Diagnostics
14	Expression
42	General Information
6	General Stability
2	IC50 Value
163	Inhibitors
4	kcat/KM [mM/s]
3	Ki Value [mM]
72	KM Value [mM]
50	Localization
54	Metals/Ions
108	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
384	Organism
12	Pathway
32	PDB ID
46	pH Optimum
3	pH Range
2	pI Value
34	Protein Variants
43	Purification (Commentary)
22	Reaction
2	Reaction Type
183	Reference
1	Renatured (Commentary)
257	Source Tissue
17	Specific Activity [micromol/min/mg]
7	Storage Stability
206	Substrates and Products (Substrate)
58	Subunits
238	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
5	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 5.5.1.4 - inositol-3-phosphate synthase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, BioGel A purified fractions (final purification fraction), 5-7 days

Homo sapiens

Q9NPH2

728988

-20°C, partially purified enzyme is stable for at least 6 months

Pinus ponderosa

-

3712

-20°C, partially purified enzyme is stable for several months

Rattus norvegicus

-

3688

-20°C, purified recombinant enzyme, 20% v/v glycerol, completely stable for several weeks

Drosophila melanogaster

-

662602

0°C, 70% loss of activity after 18 h, enzyme in crude extract. Stabilization by (NH4)2SO4 and dimethyl sulfoxide in 20% solution

Streptomyces sp.

-

3701

4°C, -20°C or -70°C, stable

Saccharomyces cerevisiae

-

3702

4°C, very stable in 0.1 M Tris-acetate buffer, pH 7.8, 14% loss of activity after 7 days and 51% loss of activity after 1 month

Cyberlindnera jadinii

-

3703