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5.5.1.4: inositol-3-phosphate synthase

This is an abbreviated version!
For detailed information about inositol-3-phosphate synthase, go to the full flat file.

Word Map on EC 5.5.1.4

Reaction

D-glucose 6-phosphate
=
1D-myo-inositol 3-phosphate

Synonyms

1D-myo-inositol 3-phosphate synthase, 1L-myo-Inositol-1-phosphate synthase, AtMIPS1, AtMIPS2-1, AtMIPS3, CaMIPS1, CaMIPS2, D-Glucose 6-phosphate cycloaldolase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cyclase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase, D-Glucose 6-phosphate-L-myo-inositol 1-phosphate cyclase, D-Glucose-6-phosphate,L-myo-inositol-1-phosphate cycloaldolase, D-myo-inositol-3-phosphate synthase, Glucocycloaldolase, Glucose 6-phosphate cyclase, Glucose-6-phosphate inositol monophosphate cycloaldolase, INO-1, INO-2, INO1, Ino1p, iNOS, Inositol 1-phosphate synthase, Inositol 1-phosphate synthetase, inositol 3-phosphate synthase, inositol phosphate synthase, inositol-1-phosphate synthase, inositol-3-phosphate synthase, INPS, INPS1, INS (3) P1 synthase, IP synthase, IPS, L-myo-inositol 1-phosphate synthase, L-myo-Inositol 1-phosphate synthetase, L-myo-Inositol-1-phosphate synthase, MI-1-P synthase, MIP synthase, MIPS, MIPS1, MIPS2, myo-D-inositol 3-phosphate synthase, myo-inositol 1-phosphate synthase, myo-inositol 3-phosphate synthase, myo-inositol phosphate synthase, myo-Inositol-1-P synthase, Myo-inositol-1-phosphate synthase, myo-inositol-3-phosphate synthase, OsMIPS1, OsMIPS1-1, OsMIPS1-2, OsMIPS1-3, OsMIPS2, PcINO1, PINO1 protein, PIP synthase, PIPS, RINO1 protein, SaINO1, sll1981, Synthase, myo-inositol 1-phosphate, TaMIPS1, TaMIPS2, tbINO, yMIP synthase, [Ins(3)P1] synthase

ECTree

     5 Isomerases
         5.5 Intramolecular lyases
             5.5.1 Intramolecular lyases (only sub-subclass identified to date)
                5.5.1.4 inositol-3-phosphate synthase

Disease

topprint

Disease on EC 5.5.1.4 - inositol-3-phosphate synthase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Alzheimer Disease
The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles.
Brain Neoplasms
Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors.
klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division.
Breast Neoplasms
Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity.
Carcinoma
Improving drug accumulation and photothermal efficacy in tumor depending on size of ICG loaded lipid-polymer nanoparticles.
Cardiotoxicity
Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity.
Dehydration
Ectopic expression of the ABA-inducible dehydration-responsive chickpea L-myo-inositol 1-phosphate synthase 2 (CaMIPS2) in Arabidopsis enhances tolerance to salinity and dehydration stress.
Importance of inositols and their derivatives in cowpea under root dehydration: An omics perspective.
Glioma
Distributions of intravenous injected iodine nanoparticles in orthotopic u87 human glioma xenografts over time and tumor therapy.
Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma.
Infections
Minimum detectable level of Salmonellae using a binomial-based bacterial ice nucleation detection assay (BIND).
Infertility, Male
Disruption of INOS, a Gene Encoding myo-Inositol Phosphate Synthase, Causes Male Sterility in Drosophila melanogaster.
Leishmaniasis
In-silico studies on Myo inositol-1-phosphate synthase of Leishmania donovani in search of anti-leishmaniasis.
Lung Neoplasms
Antibody Conjugated PLGA Nanoparticles for Targeted Delivery of Paclitaxel Palmitate: Efficacy and Biofate in a Lung Cancer Mouse Model.
Lymphogranuloma Venereum
Candidate vaginal microbicides with activity against Chlamydia trachomatis and Neisseriagonorrhoeae.
Microcephaly
Retinoic acid controls early neurogenesis in the developing mouse cerebral cortex.
Myocardial Infarction
[Psychological and occupational repercussions of myocardial infarct]
Neoplasm Metastasis
Sentinel Lymph Node Pressure in Breast Cancer.
Neoplasms
Analyses of Intravesicular Exosomal Proteins Using a Nano-Plasmonic System.
Antibody Conjugated PLGA Nanoparticles for Targeted Delivery of Paclitaxel Palmitate: Efficacy and Biofate in a Lung Cancer Mouse Model.
Distributions of intravenous injected iodine nanoparticles in orthotopic u87 human glioma xenografts over time and tumor therapy.
Exploring naturally occurring ivy nanoparticles as an alternative biomaterial.
Improving drug accumulation and photothermal efficacy in tumor depending on size of ICG loaded lipid-polymer nanoparticles.
INPS: predicting the impact of non-synonymous variations on protein stability from sequence.
Iodine nanoparticle radiotherapy of human breast cancer growing in the brains of athymic mice.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Sentinel Lymph Node Pressure in Breast Cancer.
Updates on the applications of iron-based nanoplatforms in tumor theranostics.
Seizures
Myo-inositol-1-phosphate (MIP) synthase inhibition: in-vivo study in rats.
Trypanosomiasis, African
Screening the MayBridge Rule of 3 Fragment Library for Compounds That Interact with the Trypanosoma brucei myo-Inositol-3-Phosphate Synthase and/or Show Trypanocidal Activity.
Tuberculosis
Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis.
Identification of the INO1 gene of Mycobacterium tuberculosis H37Rv reveals a novel class of inositol-1-phosphate synthase enzyme.
Studies of inositol 1-phosphate analogues as inhibitors of the phosphatidylinositol phosphate synthase in mycobacteria.
[Organization of the 1st 9 international courses on the "Epidemiology and Control of Tuberculosis" for physicians treating tuberculosis, held at the Istituto "C. Forlanini" of the INPS of Rome]
[Report of the scientific and didactic activity of the tuberculosis clinic of the University of Rome, and the Carlo Forlanini sanatorium and study center of the INPS in the year 1965]
[SCIENTIFIC AND DIDACTIC ACTIVITIES OF THE TUBERCULOSIS CLINIC, THE CENTER OF STUDIES AND THE OSPEDALE "CARLO FORLANINI" OF THE INPS DURING THE YEAR 1964.]
[Trends in tuberculosis in the Ferrara region 1984-1987]
Tuberculosis, Pulmonary
[Observation on "1st admittance" cases of pulmonary tuberculosis in the Ospedale Sanitoriale INPS di Rovigo. (Clinico-statistical investigation related to the last 2-year period)]
[The incidence of pulmonary tuberculosis in childhood (0-12 years) in the records of the Ospedale Sanatoriale INPS of Cagliari.]