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5.5.1.19: lycopene beta-cyclase

This is an abbreviated version!
For detailed information about lycopene beta-cyclase, go to the full flat file.

Word Map on EC 5.5.1.19

Reaction

carotenoid psi-end group
=
carotenoid beta-end group

Synonyms

beta-LCY, beta-LCY1, capsanthin-capsorubin synthase, CCS, chromoplast-specific lycopene beta cyclase, CrtL, CrtL-b, CrtL-e, CrtY, crtYB, CruA, CruP, CYC-B, DcLCYB1, LCY, LCY-B, LCY-beta, LCYb, LCYb1, LCYB2, LCYb3, LCYb4, LYCB, lycopene beta cyclase, lycopene beta-cyclase 1, lycopene cyclase, phytoene synthase/lycopene cyclase, SSO2904

ECTree

     5 Isomerases
         5.5 Intramolecular lyases
             5.5.1 Intramolecular lyases (only sub-subclass identified to date)
                5.5.1.19 lycopene beta-cyclase

Reference

Reference on EC 5.5.1.19 - lycopene beta-cyclase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stickforth, P.; Steiger, S.; Hess, W.R.; Sandmann, G.
A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4
Arch. Microbiol.
179
409-415
2003
Prochlorococcus marinus, Prochlorococcus marinus MED4
Manually annotated by BRENDA team
Cunningham, F.X. Jr.; Chamovitz, D.; Misawa, N.; Gantt, E.; Hirschberg, J.
Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of beta-carotene
FEBS Lett.
328
130-138
1993
Synechococcus sp., Synechococcus sp. PCC 7942
Manually annotated by BRENDA team
Hornero-Mendez, D.; Britton, G.
Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis
FEBS Lett.
515
133-136
2002
Pantoea ananatis
Manually annotated by BRENDA team
Rodrigo, M.J.; Marcos, J.F.; Zacarías, L.
Biochemical and molecular analysis of carotenoid biosynthesis in flavedo of orange (Citrus sinensis L.) during fruit development and maturation
J. Agric. Food Chem.
52
6724-6731
2004
Citrus sinensis (Q6QM27), Citrus sinensis Osbeck (Q6QM27)
Manually annotated by BRENDA team
Cunningham, F.X. Jr.; Sun, Z.; Chamovitz, D.; Hirschberg, J.; Gantt, E.
Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942
Plant Cell
6
1107-1121
1994
Synechococcus elongatus (Q55276), Synechococcus elongatus PCC 7942 (Q55276)
Manually annotated by BRENDA team
Hugueney, P.; Badillo, A.; Chen, H.C.; Klein, A.; Hirschberg, J.; Camara, B.; Kuntz, M.
Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts
Plant J.
8
417-424
1995
Capsicum annuum (Q43415), Capsicum annuum, Capsicum annuum cv. Yolo Wonder (Q43415)
Manually annotated by BRENDA team
Pecker, I.; Gabbay, R.; Cunningham, F.X. Jr.; Hirschberg, J.
Cloning and characterization of the cDNA for lycopene beta-cyclase from tomato reveals decrease in its expression during fruit ripening
Plant Mol. Biol.
30
807-819
1996
Solanum lycopersicum (Q43503), Solanum lycopersicum
Manually annotated by BRENDA team
Mialoundama, A.S.; Heintz, D.; Jadid, N.; Nkeng, P.; Rahier, A.; Deli, J.; Camara, B.; Bouvier, F.
Characterization of plant carotenoid cyclases as members of the flavoprotein family functioning with no net redox change
Plant Physiol.
153
970-979
2010
Capsicum annuum (Q42435)
Manually annotated by BRENDA team
Maresca, J.A.; Graham, J.E.; Wu, M.; Eisen, J.A.
Bryant, D.A.: Identification of a fourth family of lycopene cyclases in photosynthetic bacteria
Proc. Natl. Acad. Sci. USA
104
11784-11789
2007
Synechococcus sp. (A5A545), Synechococcus sp. (A5A546), Synechococcus sp.
Manually annotated by BRENDA team
Araya-Garay, J.M.; Feijoo-Siota, L.; Veiga-Crespo, P.; Villa, T.G.
cDNA cloning of a novel gene codifying for the enzyme lycopene beta-cyclase from Ficus carica and its expression in Escherichia coli
Appl. Microbiol. Biotechnol.
92
769-777
2011
Ficus carica (F1JUS7), Ficus carica
Manually annotated by BRENDA team
Hemmi, H.; Ikejiri, S.; Nakayama, T.; Nishino, T.
Fusion-type lycopene beta-cyclase from a thermoacidophilic archaeon Sulfolobus solfataricus
Biochem. Biophys. Res. Commun.
305
586-591
2003
Saccharolobus solfataricus (Q97UT9), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97UT9)
Manually annotated by BRENDA team
Hao, H.; Ma, L.; Cong, H.; Li, Q.; Yu, X.
Isolation and characterization of a muskmelon cDNA encoding lycopene beta-cyclase
Gene
503
147-151
2012
Cucumis melo
Manually annotated by BRENDA team
Guo, W.; Tang, H.; Zhang, L.
Lycopene cyclase and phytoene synthase activities in the marine yeast Rhodosporidium diobovatum are encoded by a single gene crtYB
J. Basic Microbiol.
54
1053-1061
2014
Rhodotorula diobovata (T1SGQ2), Rhodotorula diobovata, Rhodotorula diobovata ATCC 2527 (T1SGQ2)
Manually annotated by BRENDA team
Jeong, T.H.; Ji, K.; Kim, Y.T.
Overexpression and characterization of lycopene cyclase (CrtY) from marine bacterium Paracoccus haeundaensis
J. Microbiol. Biotechnol.
23
144-148
2013
Paracoccus haeundaensis (Q24K62), Paracoccus haeundaensis
Manually annotated by BRENDA team
Giorio, G.; Yildirim, A.; Stigliani, A.L.; DAmbrosio, C.
Elevation of lutein content in tomato: a biochemical tug-of-war between lycopene cyclases
Metab. Eng.
20
167-176
2013
Solanum lycopersicum
Manually annotated by BRENDA team
Gao, M.; Qu, H.; Gao, L.; Chen, L.; Sebastian, R.S.; Zhao, L.
Dissecting the mechanism of Solanum lycopersicum and Solanum chilense flower colour formation
Plant Biol.
17
1-8
2014
Solanum lycopersicum, Solanum chilense, Solanum lycopersicum P86, Solanum chilense LA2405
Manually annotated by BRENDA team
Takemura, M.; Maoka, T.; Misawa, N.
Carotenoid analysis of a liverwort Marchantia polymorpha and functional identification of its lycopene beta- and epsilon-cyclase genes
Plant Cell Physiol.
55
194-200
2014
Marchantia polymorpha (W0S9F1)
Manually annotated by BRENDA team
Guo, F.; Zhou, W.; Zhang, J.; Xu, Q.; Deng, X.
Effect of the citrus lycopene beta-cyclase transgene on carotenoid metabolism in transgenic tomato fruits
PLoS ONE
7
e32221
2012
Citrus sp.
Manually annotated by BRENDA team
Moreno, J.C.; Pizarro, L.; Fuentes, P.; Handford, M.; Cifuentes, V.; Stange, C.
Levels of lycopene beta-cyclase 1 modulate carotenoid gene expression and accumulation in Daucus carota
PLoS ONE
8
e58144
2013
Daucus carota (Q2VEX7), Daucus carota
Manually annotated by BRENDA team
Zhou, P.; Xie, W.; Li, A.; Wang, F.; Yao, Z.; Bian, Q.; Zhu, Y.; Yu, H.; Ye, L.
Alleviation of metabolic bottleneck by combinatorial engineering enhanced astaxanthin synthesis in Saccharomyces cerevisiae
Enzyme Microb. Technol.
100
28-36
2017
Phaffia rhodozyma (Q7Z859), Phaffia rhodozyma CGMCC As2.1557 (Q7Z859)
Manually annotated by BRENDA team
Wu, M.; Lewis, J.; Moore, R.C.
A wild origin of the loss-of-function lycopene beta cyclase (CYC-b) allele in cultivated, red-fleshed papaya (Carica papaya)
Am. J. Bot.
104
116-126
2017
Carica papaya
Manually annotated by BRENDA team
Ukibe, K.; Hashida, K.; Yoshida, N.; Takagi, H.
Metabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance
Appl. Environ. Microbiol.
75
7205-7211
2009
Phaffia rhodozyma (Q7Z859), Phaffia rhodozyma ATCC 24202 (Q7Z859)
Manually annotated by BRENDA team
Bang, H.; Yi, G.; Kim, S.; Leskovar, D.; Patil, B.
Watermelon lycopene beta-cyclase promoter characterization leads to the development of a PCR marker for allelic selection
Euphytica
200
363-378
2014
Citrullus lanatus
-
Manually annotated by BRENDA team
Shi, Y.; Guo, J.; Zhang, W.; Jin, L.; Liu, P.; Chen, X.; Li, F.; Wei, P.; Li, Z.; Li, W.; Wei, C.; Zheng, Q.; Chen, Q.; Zhang, J.; Lin, F.; Qu, L.; Snyder, J.H.; Wang, R.
Cloning of the lycopene beta-cyclase gene in Nicotiana tabacum and its overexpression confers salt and drought tolerance
Int. J. Mol. Sci.
16
30438-30457
2015
Nicotiana tabacum
Manually annotated by BRENDA team
Moreno, J.C.; Cerda, A.; Simpson, K.; Lopez-Diaz, I.; Carrera, E.; Handford, M.; Stange, C.
Increased Nicotiana tabacum fitness through positive regulation of carotenoid, gibberellin and chlorophyll pathways promoted by Daucus carota lycopene beta-cyclase (Dclcyb1) expression
J. Exp. Bot.
67
2325-2338
2016
Daucus carota (Q2VEX7)
Manually annotated by BRENDA team
Namitha, K.; Negi, P.
Transformation of tomato cv. Arka Ahuti (Solanum lycopersicum L.) with phytoene desaturase (CrtI) and lycopene beta-cyclase (CrtY) genes increases carotenoid content and antioxidant potential
J. Plant Biochem. Biotechnol.
27
68-77
2018
Pantoea agglomerans
-
Manually annotated by BRENDA team
Cao, T.J.; Huang, X.Q.; Qu, Y.Y.; Zhuang, Z.; Deng, Y.Y.; Lu, S.
Cloning and functional characterization of a lycopene beta-cyclase from macrophytic red alga Bangia fuscopurpurea
Mar. Drugs
15
pii: E116
2017
Bangia fuscopurpurea (A0A1X9RR88)
Manually annotated by BRENDA team
Kim, S.H.; Jeong, J.C.; Park, S.; Bae, J.Y.; Ahn, M.J.; Lee, H.S.; Kwak, S.S.
Down-regulation of sweetpotato lycopene beta-cyclase gene enhances tolerance to abiotic stress in transgenic calli
Mol. Biol. Rep.
41
8137-8148
2014
Ipomoea batatas (H6TBL2)
Manually annotated by BRENDA team
Jin, C.; Ji, J.; Zhao, Q.; Ma, R.; Guan, C.; Wang, G.
Characterization of lycopene beta-cyclase gene from Lycium chinense conferring salt tolerance by increasing carotenoids synthesis and oxidative stress resistance in tobacco
Mol. Breed.
35
228
2015
Lycium chinense (A0A0U2DBC9)
-
Manually annotated by BRENDA team
Sugiyama, K.; Ebisawa, M.; Yamada, M.; Nagashima, Y.; Suzuki, H.; Maoka, T.; Takaichi, S.
Functional lycopene cyclase (CruA) in cyanobacterium, Arthrospira platensis NIES-39, and its role in carotenoid synthesis
Plant Cell Physiol.
58
831-838
2017
Arthrospira platensis, Arthrospira platensis NIES-39
Manually annotated by BRENDA team
Blatt, A.; Bauch, M.E.; Poerschke, Y.; Lohr, M.
A lycopene beta-cyclase/lycopene epsilon-cyclase/light-harvesting complex-fusion protein from the green alga Ostreococcus lucimarinus can be modified to produce alpha-carotene and beta-carotene at different ratios
Plant J.
82
582-595
2015
Ostreococcus sp. 'lucimarinus'
Manually annotated by BRENDA team
Kang, C.; Zhai, H.; Xue, L.; Zhao, N.; He, S.; Liu, Q.
A lycopene beta-cyclase gene, IbLCYB2, enhances carotenoid contents and abiotic stress tolerance in transgenic sweetpotato
Plant Sci.
272
243-254
2018
Ipomoea batatas
Manually annotated by BRENDA team
Mohan, V.; Pandey, A.; Sreelakshmi, Y.; Sharma, R.
Neofunctionalization of chromoplast specific lycopene beta cyclase gene (CYC-B) in tomato clade
PLoS ONE
11
e0153333
2016
Solanum lycopersicum, Solanum habrochaites, Solanum pimpinellifolium, Solanum pennellii, Solanum chilense, Solanum cheesmaniae, Solanum neorickii
Manually annotated by BRENDA team
Kildegaard, K.R.; Adiego-Perez, B.; Domenech Belda, D.; Khangura, J.K.; Holkenbrink, C.; Borodina, I.
Engineering of Yarrowia lipolytica for production of astaxanthin
Synth. Syst. Biotechnol.
2
287-294
2017
Phaffia rhodozyma (Q7Z859)
Manually annotated by BRENDA team
Ralley, L.; Schuch, W.; Fraser, P.D.; Bramley, P.M.
Genetic modification of tomato with the tobacco lycopene beta-cyclase gene produces high beta-carotene and lycopene fruit
Z. Naturforsch. C
71
295-301
2016
Nicotiana tabacum
Manually annotated by BRENDA team
Khan, M.Z.; Takemura, M.; Maoka, T.; Otani, M.; Misawa, N.
Carotenoid analysis of sweetpotato Ipomoea batatas and functional identification of its lycopene beta- and epsilon-cyclase genes
Z. Naturforsch. C
71
313-322
2016
Ipomoea batatas (A0A1L7NW73), Ipomoea batatas (A0A1L7NW83), Ipomoea batatas (A0A1L7NW92)
Manually annotated by BRENDA team
Yang, Y.; Zhang, J.; Zhang, H.; Zhang, S.; Jia, H.; Cui, H.
Effects of overexpression lycopene beta-cyclase gene on carotenoids metabolism and aroma compounds in tobacco
Zhongguo Yan Cao Xue Bao
22
94-100
2016
Nicotiana tabacum (A0A067YF54)
-
Manually annotated by BRENDA team