5.5.1.19: lycopene beta-cyclase

This is an abbreviated version!
For detailed information about lycopene beta-cyclase, go to the full flat file.

Reaction

Synonyms

beta-LCY, beta-LCY1, capsanthin-capsorubin synthase, CCS, chromoplast-specific lycopene beta cyclase, CrtL, CrtL-b, CrtL-e, CrtY, crtYB, CruA, CruP, CYC-B, DcLCYB1, LCY, LCY-B, LCY-beta, LCYb, LCYb1, LCYB2, LCYb3, LCYb4, LYCB, lycopene beta cyclase, lycopene beta-cyclase 1, lycopene cyclase, phytoene synthase/lycopene cyclase, SSO2904

ECTree

     5 Isomerases

         5.5 Intramolecular lyases

             5.5.1 Intramolecular lyases (only sub-subclass identified to date)

                5.5.1.19 lycopene beta-cyclase

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Results	in table
1	Activating Compound
1286	AA Sequence
2	Application
30	Cloned(Commentary)
3	Cofactor
4	Expression
23	General Information
4	Inhibitors
1	KM Value [mM]
26	Localization
6	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
78	Organism
13	Pathway
2	pH Optimum
5	pI Value
10	Protein Variants
3	Purification (Commentary)
1	Reaction
56	Reference
45	Source Tissue
2	Specific Activity [micromol/min/mg]
71	Substrates and Products (Substrate)
12	Subunits
85	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Engineering

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Engineering on EC 5.5.1.19 - lycopene beta-cyclase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

D127A

Capsicum annuum

Q42435

the mutation drastically reduces the lycopene cyclase activity of CCS up to 90%

716601

D259A

Capsicum annuum

Q42435

the mutation drastically reduces the lycopene cyclase activity of CCS up to 90%

716601

E128A

Capsicum annuum

Q42435

the mutation drastically reduces the lycopene cyclase activity of CCS up to 90%

716601

E296A

Capsicum annuum

Q42435

the mutation reduces the lycopene cyclase activity of CCS

716601

E332A

Capsicum annuum

Q42435

the mutation drastically reduces the lycopene cyclase activity of CCS up to 90%

716601

down

Solanum lycopersicum

Q43503

the level of CrtL mRNA decreases at this stage of fruit ripening. Hence, the accumulation of lycopene in tomato fruits is due to a down-regulation of the lycopene cyclase gene that occurs at the breaker stage of fruit development

716556

additional information

5 entries

additional information

Daucus carota

Q2VEX7

posttranscriptional gene silencing of gene DcLcyb1 in carrot affects carotenoid levels and endogenous carotenoid gene expression, overview

728593

additional information

Daucus carota

-

posttranscriptional gene silencing of gene DcLcyb1 in carrot affects carotenoid levels and endogenous carotenoid gene expression, overview

728593

additional information

Solanum lycopersicum

-

for production of lutein in tomato fruits, it is required to overcome the enzyme downregulation before fruit ripening exhibited through a tightly regulated physiological mechanism in tomato fruits by overexpression of lycopene epsilon- and beta-cyclases in leaves and ripe fruits, carotene profile and contents, overview

728241

additional information

Synechococcus elongatus

Q55276

mutation that confers resistance to 2-(4-methylphenoxy)triethylamine hydrochloride in Synechococcus sp PCC7942 is identified as a point mutation in the promoter region of crtL

716524

additional information

Synechococcus elongatus PCC 7942

-

mutation that confers resistance to 2-(4-methylphenoxy)triethylamine hydrochloride in Synechococcus sp PCC7942 is identified as a point mutation in the promoter region of crtL

-