5.5.1.18: lycopene epsilon-cyclase
This is an abbreviated version!
For detailed information about lycopene epsilon-cyclase, go to the full flat file.
Word Map on EC 5.5.1.18
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5.5.1.18
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lutein
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phytoene
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beta-cyclase
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carotenogenesis
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provitamin
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violaxanthin
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epoxidase
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carotenogenic
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delta-carotene
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alpha-carotene
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carotene
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xanthophyl
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beta-cryptoxanthin
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neoxanthin
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osbeck
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biofortification
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crtiso
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apocarotenoids
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beta-ring
- 5.5.1.18
- lutein
- phytoene
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beta-cyclase
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carotenogenesis
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provitamin
- violaxanthin
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epoxidase
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carotenogenic
- delta-carotene
- alpha-carotene
- carotene
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xanthophyl
- beta-cryptoxanthin
- neoxanthin
- osbeck
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biofortification
- crtiso
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apocarotenoids
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beta-ring
Reaction
Synonyms
CrtL-e, epsilon lycopene cyclase, epsilon-ionone-forming lycopene cyclase, epsilon-LCY, epsilon-LCY1, epsilon-LCY2, epsilon-LYC, LCY-E, LCYe, LYCe, lycopene bi-epsilon-cyclase, lycopene epsilon cyclase, lycopene-epsilon-cyclase, OsLCYe
ECTree
5.5.1.18 lycopene epsilon-cyclaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 5.5.1.18 - lycopene epsilon-cyclase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
lycopene
delta-carotene
the cyclization of lycopene (psi,psi-carotene) is a key branch point in the pathway of carotenoid biosynthesis
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?
lycopene
delta-carotene
wild-type enzyme and mutant enzyme A447D acts one psi end of lycopene and forms monocyclic delta-carotene. Mutant enzymes L448H and L448R add two epsilon-ring to lycopene, forming epsilon-carotene
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?
lycopene
delta-carotene
lycopene epsilon-cyclase adds one epsilon-ring to synthesize delta-carotene, (6R)-epsilon,psi-carotene
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-
?
lycopene
delta-carotene + beta-carotene + alpha-carotene + epsilon-carotene
the enzyme OsLCYe catalyzes the formation of beta-carotene or delta-carotene from lycopene, and as side activities the formation of gamma-, alpha-, or epsilon-carotene from lycopene, reactions catalyzed by OsLCYe, overview
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-
?
lycopene
delta-carotene + beta-carotene + alpha-carotene + epsilon-carotene
the enzyme OsLCYe catalyzes the formation of beta-carotene or delta-carotene from lycopene, and as side actities the formation of gamma-, alpha-, or epsilon-carotene from lycopene, reactions catalyzed by OsLCYe, overview
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?
lycopene
epsilon-carotene
the enzyme acts on both psi ends of lycopene, forming bicyclic epsilon-carotene. Mutant enzyme H457L adds only one epsilon-ring to lycopene, forming delta-carotene
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-
?
lycopene
epsilon-carotene
the enzyme acts on both psi ends of lycopene, forming bicyclic epsilon-carotene. Mutant enzyme H457L adds only one epsilon-ring to lycopene, forming delta-carotene
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?
lycopene
epsilon-carotene
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bifunctional enzyme catalyzing the formation of epsilon- as well as of beta-ionone end groups
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?
lycopene
epsilon-carotene
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bifunctional enzyme catalyzing the formation of epsilon- as well as of beta-ionone end groups
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?
additional information
?
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5-cis-lycopene is not involved in the reaction with OsLCYe acting as an exclusion filter for this naturally occurring isomer. Using liposomes containing 5-cis-lycopene, OsLCYe produces the same moncyclic gamma/delts-carotene pattern as with all-trans-lycopene
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?
additional information
?
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5-cis-lycopene is not involved in the reaction with OsLCYe acting as an exclusion filter for this naturally occurring isomer. Using liposomes containing 5-cis-lycopene, OsLCYe produces the same moncyclic gamma/delts-carotene pattern as with all-trans-lycopene
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-
?
additional information
?
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purified rice LCYe enzyme in a liposome-based biphasic assay system, formation of C4-C5 epsilon-ionone rings. The enzyme from rice produces predominantly monocyclic products and shows very strong OsLCYe activity in vitro. Monocyclic carotene intermediates are not suitable substrates, no activity with 5-cis-lycopene
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-
?
additional information
?
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purified rice LCYe enzyme in a liposome-based biphasic assay system, formation of C4-C5 epsilon-ionone rings. The enzyme from rice produces predominantly monocyclic products and shows very strong OsLCYe activity in vitro. Monocyclic carotene intermediates are not suitable substrates, no activity with 5-cis-lycopene
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?
