5.5.1.11: dichloromuconate cycloisomerase

This is an abbreviated version!
For detailed information about dichloromuconate cycloisomerase, go to the full flat file.

Reaction

2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate

Synonyms

dichloromuconate cycloisomerase, isomerase, dichloromuconate cyclo-

ECTree

5 Isomerases

5.5 Intramolecular lyases

5.5.1 Intramolecular lyases (only sub-subclass identified to date)

5.5.1.11 dichloromuconate cycloisomerase

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Results	in table
1	CAS Registry Number
1	Cofactor
5	Inhibitors
7	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
52	Organism
4	Pathway
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
4	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
15	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
7	Turnover Number [1/s]

Turnover Number

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Turnover Number on EC 5.5.1.11 - dichloromuconate cycloisomerase

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63.7

2,4-dichloro-cis,cis-muconate

Cupriavidus necator

648898

15.8

2-chloro-cis,cis-muconate

Cupriavidus necator

648898

10.2

2-methyl-cis,cis-muconate

Cupriavidus necator

648898

119

3-chloro-cis,cis-muconate

Cupriavidus necator

648898

54.8

3-methyl-cis,cis-muconate

Cupriavidus necator

648898

51.5

cis,cis-muconate

Cupriavidus necator

648898

additional information

Cupriavidus necator

kcat of 2-chloro-4-methyl-cis,cis-musconate is about 55% of that found for 2,4-dichloro-cis,cis-musconate

648899