5.5.1.1: Muconate cycloisomerase

This is an abbreviated version!
For detailed information about Muconate cycloisomerase, go to the full flat file.

Word Map on EC 5.5.1.1

5.5.1.1

muconolactone

beta-ketoadipate

cycloisomerization

protoanemonin

5-chloromuconolactone

maleylacetate

2-chloro-cis,cis-muconate

cutaneum

cis-dienelactone

chlorocatechols

o-succinylbenzoate

4-chlorophenol

5.3.3.4

3-chloro

4-chlorocatechol

gerlt

phenol-degrading

ortho-cleavage

trans-dienelactone

Reaction

Synonyms

(chloro)-muconate cycloisomerase, (chloro)muconate cycloisomerase, 2-chloromuconate cycloisomerase, ADP1, anti-MLE, CatB, cis,cis-Muconate cycloisomerase, cis,cis-muconate lactonizing enzyme, cis,cis-Muconate-lactonizing enzyme, Enzymes, muconate-lactonizing, Isomerase, muconate cyclo-, MC, MC II, MC O, MCI, MCIase, MCIccaB, MLE, MLE-1, MLE-2, MLEI, muconate cycloisomerase, Muconate cycloisomerase I, Muconate lactonizing enzyme, Rho-2-CMCI, syn-MLE, TcMLE

ECTree

5 Isomerases

5.5 Intramolecular lyases

5.5.1 Intramolecular lyases (only sub-subclass identified to date)

5.5.1.1 Muconate cycloisomerase

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Results	in table
2	Activating Compound
684	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
13	Crystallization (Commentary)
15	Inhibitors
3	kcat/KM [mM/s]
5	Ki Value [mM]
94	KM Value [mM]
20	Metals/Ions
24	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
130	Organism
9	Pathway
56	PDB ID
8	pH Optimum
7	pH Range
1	pH Stability
17	Protein Variants
27	Purification (Commentary)
9	Reaction
4	Reaction Type
68	Reference
19	Source Tissue
15	Specific Activity [micromol/min/mg]
7	Storage Stability
201	Substrates and Products (Substrate)
24	Subunits
48	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
10	Temperature Stability [°C]
80	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 5.5.1.1 - Muconate cycloisomerase

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169000

Cutaneotrichosporon cutaneum

gel filtration

3646

220000

Pseudomonas putida

2972

230000 - 250000

Rhodococcus erythropolis

nondenaturing electrophoresis, gel filtration

3656

236000

Rhodococcus rhodochrous

gel filtration

651382

248500 - 260000

Pseudomonas putida

sedimentation equilibrium studies, gel filtration

280000

gel filtration

350000

gel filtration

39760

subunit, calculated from amino acid sequence

40000

400000

40248

x * 40248, calculated

680483

40926

Arthrobacter sp.

6 * 43000, SDS-PAGE, 6 * 40926, calculated

661780

41076

Pseudomonas sp.

x * 41076, calculated, x * 42000, SDS-PAGE

42000

43000

44000

x * 44000, SDS-PAGE

48000

Cutaneotrichosporon cutaneum

1 * 48000, SDS-PAGE

3638

52000

Cutaneotrichosporon cutaneum

gel filtration

3638