Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

5.4.99.9: UDP-galactopyranose mutase

This is an abbreviated version!
For detailed information about UDP-galactopyranose mutase, go to the full flat file.

Word Map on EC 5.4.99.9

Reaction

UDP-alpha-D-galactopyranose
=
UDP-alpha-D-galactofuranose

Synonyms

AfUGM, ANIA_03112, CdUGM, galactopyranose mutase, Glf, GLF gene product, GLF-1, glfA, MtUGM, mutase, Mutase, uridine diphosphogalactopyranose, TcUGM, UDP galactopyranose mutase, UDP-D-galactopyranose mutase, UDP-Gal mutase, UDP-galactopyranose mutase, UDP-Galp mutase, UGM, UgmA, UNGM, uridine 5'-diphosphate galactopyranose mutase, uridine 5'-diphosphate galactopyranosemutase, uridine 5'-diphosphate-galactopyranose mutase, uridine diphosphate galactopyranose mutase

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.9 UDP-galactopyranose mutase

Reference

topprint

Reference on EC 5.4.99.9 - UDP-galactopyranose mutase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lee, R.; Monsey, D.; Weston, A.; Duncan, K.; Rithner, C.; McNeil, M.
Enzymic synthesis of UDP-galactofuranose and an assay for UDP-galactopyranose mutase based on high-performance liquid chromatography
Anal. Biochem.
242
1-7
1996
Escherichia coli
Manually annotated by BRENDA team
Köplin, R.; Brisson, J.R.; Whitfield, C.
UDP-galactofuranose precursor required for formation of the lipopolysaccharide O antigen of Klebsiella pneumoniae serotype O1 is synthesized by the product of the rfbDKPO1 gene
J. Biol. Chem.
272
4121-4128
1997
Klebsiella pneumoniae
Manually annotated by BRENDA team
McMahon, S.A.; Leonard, G.A.; Buchanan, L.V.; Giraud, M.F.; Naismith, J.H.
Initiating a crystallographic study of UDP-galactopyranose mutase from Escherichia coli
Acta Crystallogr. Sect. D
55
399-402
1999
Escherichia coli
-
Manually annotated by BRENDA team
Fullerton, S.W.; Daff, S.; Sanders, D.A.; Ingledew, W.J.; Whitfield, C.; Chapman, S.K.; Naismith, J.H.
Potentiometric analysis of UDP-galactopyranose mutase: stabilization of the flavosemiquinone by substrate
Biochemistry
42
2104-2109
2003
Klebsiella pneumoniae
Manually annotated by BRENDA team
Zhang, Q.; Liu, H.w.
Studies of UDP-galactopyranose mutase from Escherichia coli: An unusual role of reduced FAD in its catalysis
J. Am. Chem. Soc.
122
9065-9070
2000
Escherichia coli
-
Manually annotated by BRENDA team
Sanders, D.A.; Staines, A.G.; McMahon, S.A.; McNeil, M.R.; Whitfield, C.; Naismith, J.H.
UDP-galactopyranose mutase has a novel structure and mechanism
Nat. Struct. Biol.
8
858-863
2001
Klebsiella pneumoniae, Escherichia coli (P37747), Escherichia coli
Manually annotated by BRENDA team
Bakker, H.; Kleczka, B.; Gerardy-Schahn, R.; Routier, F.H.
Identification and partial characterization of two eukaryotic UDP-galactopyranose mutases
Biol. Chem.
386
657-661
2005
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus, Leishmania major (Q5EEK0), Leishmania major
Manually annotated by BRENDA team
Caravano, A.; Sinay, P.; Vincent, S.P.
1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion
Bioorg. Med. Chem. Lett.
16
1123-1125
2006
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Beverley, S.M.; Owens, K.L.; Showalter, M.; Griffith, C.L.; Doering, T.L.; Jones, V.C.; McNeil, M.R.
Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens
Eukaryot. Cell
4
1147-1154
2005
Caenorhabditis elegans, Leishmania major (Q5EEK0), Trypanosoma cruzi (Q5EEK1), Cryptococcus neoformans (Q5KEL8)
Manually annotated by BRENDA team
Soltero-Higgin, M.; Carlson, E.E.; Phillips, J.H.; Kiessling, L.L.
Identification of inhibitors for UDP-galactopyranose mutase
J. Am. Chem. Soc.
126
10532-10533
2004
Klebsiella pneumoniae
Manually annotated by BRENDA team
Beis, K.; Srikannathasan, V.; Liu, H.; Fullerton, S.W.; Bamford, V.A.; Sanders, D.A.; Whitfield, C.; McNeil, M.R.; Naismith, J.H.
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state
J. Mol. Biol.
348
971-982
2005
Klebsiella pneumoniae, Mycobacterium tuberculosis
Manually annotated by BRENDA team
Soltero-Higgin, M.; Carlson, E.E.; Gruber, T.D.; Kiessling, L.L.
A unique catalytic mechanism for UDP-galactopyranose mutase
Nat. Struct. Mol. Biol.
11
539-543
2004
Klebsiella pneumoniae
Manually annotated by BRENDA team
Chad, J.M.; Sarathy, K.P.; Gruber, T.D.; Addala, E.; Kiessling, L.L.; Sanders, D.A.
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues
Biochemistry
46
6723-6732
2007
Klebsiella pneumoniae (Q48485), Klebsiella pneumoniae
Manually annotated by BRENDA team
Carlson, E.E.; May, J.F.; Kiessling, L.L.
Chemical probes of UDP-galactopyranose mutase
Chem. Biol.
13
825-837
2006
Klebsiella pneumoniae
Manually annotated by BRENDA team
Caravano, A.; Dohi, H.; Sinay, P.; Vincent, S.P.
A new methodology for the synthesis of fluorinated exo-glycals and their time-dependent inhibition of UDP-galactopyranose mutase
Chemistry
12
3114-3123
2006
Escherichia coli
Manually annotated by BRENDA team
Kleczka, B.; Lamerz, A.C.; van Zandbergen, G.; Wenzel, A.; Gerardy-Schahn, R.; Wiese, M.; Routier, F.H.
Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence
J. Biol. Chem.
282
10498-10505
2007
Leishmania major
Manually annotated by BRENDA team
Eppe, G.; Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrieres, V.; Vincent, S.P.
Probing UDP-galactopyranose mutase binding pocket: A dramatic effect on substitution of the 6-position of UDP-galactofuranose
Bioorg. Med. Chem. Lett.
19
814-816
2008
Escherichia coli, Mycobacterium tuberculosis
Manually annotated by BRENDA team
Schmalhorst, P.S.; Krappmann, S.; Vervecken, W.; Rohde, M.; Mueller, M.; Braus, G.H.; Contreras, R.; Braun, A.; Bakker, H.; Routier, F.H.
Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus
Eukaryot. Cell
7
1268-1277
2008
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus
Manually annotated by BRENDA team
El-Ganiny, A.M.; Sanders, D.A.; Kaminskyj, S.G.
Aspergillus nidulans UDP-galactopyranose mutase, encoded by ugmA plays key roles in colony growth, hyphal morphogenesis, and conidiation
Fungal Genet. Biol.
45
1533-1542
2008
Aspergillus nidulans
Manually annotated by BRENDA team
Damveld, R.A.; Franken, A.; Arentshorst, M.; Punt, P.J.; Klis, F.M.; van den Hondel, C.A.; Ram, A.F.
A novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis
Genetics
178
873-881
2008
Aspergillus niger, Aspergillus niger RD6.13
Manually annotated by BRENDA team
Yuan, Y.; Bleile, D.W.; Wen, X.; Sanders, D.A.; Itoh, K.; Liu, H.W.; Pinto, B.M.
Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations
J. Am. Chem. Soc.
130
3157-3168
2008
Klebsiella pneumoniae (Q48485), Klebsiella pneumoniae
Manually annotated by BRENDA team
Dykhuizen, E.C.; May, J.F.; Tongpenyai, A.; Kiessling, L.L.
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth
J. Am. Chem. Soc.
130
6706-6707
2008
Klebsiella pneumoniae, Mycobacterium tuberculosis, Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Liautard, V.; Desvergnes, V.; Itoh, K.; Liu, H.W.; Martin, O.R.
Convergent and stereoselective synthesis of iminosugar-containing Galf and UDP-Galf mimicks: evaluation as inhibitors of UDP-Gal mutase
J. Org. Chem.
73
3103-3115
2008
Escherichia coli
Manually annotated by BRENDA team
Dykhuizen, E.C.; Kiessling, L.L.
Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite
Org. Lett.
11
193-196
2009
Klebsiella pneumoniae, Mycobacterium tuberculosis
Manually annotated by BRENDA team
Yao, X.; Bleile, D.W.; Yuan, Y.; Chao, J.; Sarathy, K.P.; Sanders, D.A.; Pinto, B.M.; ONeill, M.A.
Substrate directs enzyme dynamics by bridging distal sites: UDP-galactopyranose mutase
Proteins
74
972-979
2008
Klebsiella pneumoniae
Manually annotated by BRENDA team
Karunan Partha, S.; Bonderoff, S.A.; van Straaten, K.E.; Sanders, D.A.
Expression, purification and preliminary X-ray crystallographic analysis of UDP-galactopyranose mutase from Deinococcus radiodurans
Acta Crystallogr. Sect. F
65
843-845
2009
Deinococcus radiodurans
Manually annotated by BRENDA team
Gruber, T.D.; Westler, W.M.; Kiessling, L.L.; Forest, K.T.
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin
Biochemistry
48
9171-9173
2009
Mycobacterium tuberculosis (P9WIQ1), Mycobacterium tuberculosis
Manually annotated by BRENDA team
Novelli, J.F.; Chaudhary, K.; Canovas, J.; Benner, J.S.; Madinger, C.L.; Kelly, P.; Hodgkin, J.; Carlow, C.K.
Characterization of the Caenorhabditis elegans UDP-galactopyranose mutase homolog glf-1 reveals an essential role for galactofuranose metabolism in nematode surface coat synthesis
Dev. Biol.
335
340-355
2009
Caenorhabditis elegans, Caenorhabditis elegans N2
Manually annotated by BRENDA team
Caravano, A.; Vincent, S.
Synthesis of three C-glycoside analogues of UDP-galactopyranose as conformational probes for the mutase-catalyzed furanose/pyranose interconversion
Eur. J. Org. Chem.
2009
1771-1780
2009
Escherichia coli
-
Manually annotated by BRENDA team
Poulin, M.B.; Nothaft, H.; Hug, I.; Feldman, M.F.; Szymanski, C.M.; Lowary, T.L.
Characterization of a bifunctional pyranose-furanose mutase from Campylobacter jejuni 11168
J. Biol. Chem.
285
493-501
2010
Campylobacter jejuni, Campylobacter jejuni 11168
Manually annotated by BRENDA team
Gruber, T.D.; Borrok, M.J.; Westler, W.M.; Forest, K.T.; Kiessling, L.L.
Ligand binding and substrate discrimination by UDP-galactopyranose mutase
J. Mol. Biol.
391
327-340
2009
Klebsiella pneumoniae (Q48485), Klebsiella pneumoniae
Manually annotated by BRENDA team
Partha, S.K.; van Straaten, K.E.; Sanders, D.A.
Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP
J. Mol. Biol.
394
864-877
2009
Deinococcus radiodurans
Manually annotated by BRENDA team
Errey, J.C.; Mann, M.C.; Fairhurst, S.A.; Hill, L.; McNeil, M.R.; Naismith, J.H.; Percy, J.M.; Whitfield, C.; Field, R.A.
Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria
Org. Biomol. Chem.
7
1009-1016
2009
Klebsiella pneumoniae
Manually annotated by BRENDA team
Sadeghi-Khomami, A.; Forcada, T.J.; Wilson, C.; Sanders, D.A.; Thomas, N.R.
The UDP-Galp mutase catalyzed isomerization: synthesis and evaluation of 1,4-anhydro-beta-D-galactopyranose and its [2.2.2] methylene homologue
Org. Biomol. Chem.
8
1596-1602
2010
Klebsiella pneumoniae
Manually annotated by BRENDA team
Yao, X.; Bleile, D.; Yuan, Y.; Chao, J.; Sarathy, K.; Sanders, D.; Pinto, B.; O’Neill, M.
Substrate directs enzyme dynamics by bridging distal sites: UDP-galactopyranose mutase
Proteins Struct. Funct. Bioinform.
74
972-979
2009
Klebsiella pneumoniae
Manually annotated by BRENDA team
Oppenheimer, M.; Poulin, M.B.; Lowary, T.L.; Helm, R.F.; Sobrado, P.
Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus
Arch. Biochem. Biophys.
502
31-38
2010
Aspergillus fumigatus
Manually annotated by BRENDA team
Oppenheimer, M.; Valenciano, A.L.; Sobrado, P.
Isolation and characterization of functional Leishmania major virulence factor UDP-galactopyranose mutase
Biochem. Biophys. Res. Commun.
407
552-556
2011
Leishmania major
Manually annotated by BRENDA team
Paul, B.C.; El-Ganiny, A.M.; Abbas, M.; Kaminskyj, S.G.; Dahms, T.E.
Quantifying the importance of galactofuranose in Aspergillus nidulans hyphal wall surface organization by atomic force microscopy
Eukaryot. Cell
10
646-653
2011
Aspergillus nidulans
Manually annotated by BRENDA team
Borrelli, S.; Zandberg, W.F.; Mohan, S.; Ko, M.; Martinez-Gutierrez, F.; Partha, S.K.; Sanders, D.A.; Av-Gay, Y.; Pinto, B.M.
Antimycobacterial activity of UDP-galactopyranose mutase inhibitors
Int. J. Antimicrob. Agents
36
364-368
2010
Klebsiella pneumoniae, Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Partha, S.K.; Sadeghi-Khomami, A.; Slowski, K.; Kotake, T.; Thomas, N.R.; Jakeman, D.L.; Sanders, D.A.
Chemoenzymatic synthesis, inhibition studies, and X-ray crystallographic analysis of the phosphono analog of UDP-Galp as an inhibitor and mechanistic probe for UDP-galactopyranose mutase
J. Mol. Biol.
403
578-590
2010
Klebsiella pneumoniae, Mycobacterium tuberculosis, Deinococcus radiodurans (Q9RYF1), Deinococcus radiodurans
Manually annotated by BRENDA team
Penman, G.A.; Lockhart, D.E.; Ferenbach, A.; van Aalten, D.M.
Purification, crystallization and preliminary X-ray diffraction data of UDP-galactopyranose mutase from Aspergillus fumigatus
Acta Crystallogr. Sect. F
68
705-708
2012
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus
Manually annotated by BRENDA team
Tanner, J.J.; Boechi, L.; Andrew McCammon, J.; Sobrado, P.
Structure, mechanism, and dynamics of UDP-galactopyranose mutase
Arch. Biochem. Biophys.
544
128-141
2014
Aspergillus fumigatus, Deinococcus radiodurans, Escherichia coli, Klebsiella pneumoniae, Leishmania infantum, Leishmania major, Leishmania mexicana, Mycobacterium tuberculosis, Trypanosoma cruzi, Deinococcus radiodurans R1 / ATCC 13939 / DSM 20539
Manually annotated by BRENDA team
Poulin, M.B.; Shi, Y.; Protsko, C.; Dalrymple, S.A.; Sanders, D.A.; Pinto, B.M.; Lowary, T.L.
Specificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infections
ChemBioChem
15
47-56
2014
Campylobacter jejuni, Campylobacter jejuni 11168
Manually annotated by BRENDA team
Qi, J.; Oppenheimer, M.; Sobrado, P.
Fluorescence polarization binding assay for Aspergillus fumigatus virulence factor UDP-galactopyranose mutase
Enzyme Res.
2011
513905
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
van Straaten, K.E.; Routier, F.H.; Sanders, D.A.
Structural insight into the unique substrate binding mechanism and flavin redox state of UDP-galactopyranose mutase from Aspergillus fumigatus
J. Biol. Chem.
287
10780-10790
2012
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus
Manually annotated by BRENDA team
Sun, H.G.; Ruszczycky, M.W.; Chang, W.C.; Thibodeaux, C.J.; Liu, H.W.
Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase
J. Biol. Chem.
287
4602-4608
2012
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Boechi, L.; de Oliveira, C.A.; Da Fonseca, I.; Kizjakina, K.; Sobrado, P.; Tanner, J.J.; McCammon, J.A.
Substrate-dependent dynamics of UDP-galactopyranose mutase: implications for drug design
Protein Sci.
22
1490-1501
2013
no activity in Homo sapiens, Trypanosoma cruzi
Manually annotated by BRENDA team
Kincaid, V.A.; London, N.; Wangkanont, K.; Wesener, D.A.; Marcus, S.A.; Heroux, A.; Nedyalkova, L.; Talaat, A.M.; Forest, K.T.; Shoichet, B.K.; Kiessling, L.L.
Virtual screening for UDP-galactopyranose mutase ligands identifies a new class of antimycobacterial agents
ACS Chem. Biol.
10
2209-2218
2015
Caenorhabditis elegans, Mycobacterium tuberculosis, Klebsiella pneumoniae (Q48485), Corynebacterium diphtheriae (Q6NER4)
Manually annotated by BRENDA team
Sobrado, P.; Tanner, J.J.
Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase
Arch. Biochem. Biophys.
632
59-65
2017
Aspergillus fumigatus (Q4W1X2)
Manually annotated by BRENDA team
Martin Del Campo, J.S.; Eckshtain-Levi, M.; Sobrado, P.
Identification of eukaryotic UDP-galactopyranose mutase inhibitors using the ThermoFAD assay
Biochem. Biophys. Res. Commun.
493
58-63
2017
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus, Mycobacterium tuberculosis
Manually annotated by BRENDA team
Da Fonseca, I.; Qureshi, I.A.; Mehra-Chaudhary, R.; Kizjakina, K.; Tanner, J.J.; Sobrado, P.
Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics
Biochemistry
53
7794-7804
2014
Mycobacterium tuberculosis, Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus, Trypanosoma cruzi (Q5EEK1), Trypanosoma cruzi
Manually annotated by BRENDA team
Mehra-Chaudhary, R.; Dai, Y.; Sobrado, P.; Tanner, J.J.
In crystallo capture of a covalent intermediate in the UDP-galactopyranose mutase reaction
Biochemistry
55
833-836
2016
Aspergillus fumigatus (Q4W1X2)
Manually annotated by BRENDA team
Wangkanont, K.; Winton, V.J.; Forest, K.T.; Kiessling, L.L.
Conformational control of UDP-galactopyranose mutase inhibition
Biochemistry
56
3983-3992
2017
Corynebacterium diphtheriae (Q6NER4), Corynebacterium diphtheriae
Manually annotated by BRENDA team
Pierdominici-Sottile, G.; Cossio-Perez, R.; Da Fonseca, I.; Kizjakina, K.; Tanner, J.J.; Sobrado, P.
Steric control of the rate-limiting step of UDP-galactopyranose mutase
Biochemistry
57
3713-3721
2018
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus
Manually annotated by BRENDA team
Kuppala, R.; Borrelli, S.; Slowski, K.; Sanders, D.A.; Ravindranathan Kartha, K.P.; Pinto, B.M.
Synthesis and biological evaluation of nonionic substrate mimics of UDP-Galp as candidate inhibitors of UDP galactopyranose mutase (UGM)
Bioorg. Med. Chem. Lett.
25
1995-1997
2015
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Mahdavi-Amiri, Y.; Mohan, S.; Borrelli, S.; Slowski, K.; Sanders, D.A.; Pinto, B.M.
Mechanism-based candidate inhibitors of uridine diphosphate galactopyranose mutase (UGM)
Carbohydr. Res.
419
1-7
2016
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Shi, Y.; Colombo, C.; Kuttiyatveetil, J.R.; Zalatar, N.; van Straaten, K.E.; Mohan, S.; Sanders, D.A.; Pinto, B.M.
A second, druggable binding site in UDP-galactopyranose mutase from Mycobacterium tuberculosis?
ChemBioChem
17
2264-2273
2016
Mycobacterium tuberculosis
Manually annotated by BRENDA team
van Straaten, K.E.; Kuttiyatveetil, J.R.; Sevrain, C.M.; Villaume, S.A.; Jimenez-Barbero, J.; Linclau, B.; Vincent, S.P.; Sanders, D.A.
Structural basis of ligand binding to UDP-galactopyranose mutase from Mycobacterium tuberculosis using substrate and tetrafluorinated substrate analogues
J. Am. Chem. Soc.
137
1230-1244
2015
Mycobacterium tuberculosis (P9WIQ1), Mycobacterium tuberculosis
Manually annotated by BRENDA team
Pierdominici-Sottile, G.; Cossio Perez, R.; Galindo, J.F.; Palma, J.
QM/MM molecular dynamics study of the galactopyranose -> galactofuranose reaction catalysed by Trypanosoma cruzi UDP-galactopyranose mutase
PLoS ONE
9
e109559
2014
Trypanosoma cruzi
Manually annotated by BRENDA team
Alam, M.K.; van Straaten, K.E.; Sanders, D.A.; Kaminskyj, S.G.
Aspergillus nidulans cell wall composition and function change in response to hosting several Aspergillus fumigatus UDP-galactopyranose mutase activity mutants
PLoS ONE
9
e85735
2014
Aspergillus fumigatus (Q4W1X2), Aspergillus fumigatus, Aspergillus nidulans (Q5B8L8), Aspergillus nidulans, Aspergillus nidulans FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139 (Q5B8L8)
Manually annotated by BRENDA team