5.4.99.9: UDP-galactopyranose mutase
This is an abbreviated version!
For detailed information about UDP-galactopyranose mutase, go to the full flat file.
Word Map on EC 5.4.99.9
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5.4.99.9
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phosphoglycerate
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methylmalonic
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methylmalonyl-coa
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udp-galactofuranose
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galactofuranose
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chorismate
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urogenital
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udp-galf
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acidemia
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galf
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adenosylcobalamin
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methylmalonyl-coenzyme
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sinus
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prephenate
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acidurias
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succinyl-coa
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b12-dependent
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2,3-bisphosphoglycerate
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bisphosphoglycerate
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flavoenzyme
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adocbl
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cobalamin-dependent
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propionyl-coa
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adenosylcobalamin-dependent
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drug development
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isobutyryl-coa
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cofactor-dependent
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shermanii
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cytodifferentiation
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methylcobalamin
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phosphoenzyme
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cobiialamin
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analysis
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medicine
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synthesis
- 5.4.99.9
- phosphoglycerate
-
methylmalonic
- methylmalonyl-coa
- udp-galactofuranose
-
galactofuranose
- chorismate
-
urogenital
-
udp-galf
- acidemia
-
galf
- adenosylcobalamin
-
methylmalonyl-coenzyme
-
sinus
- prephenate
- acidurias
- succinyl-coa
-
b12-dependent
- 2,3-bisphosphoglycerate
-
bisphosphoglycerate
-
flavoenzyme
-
adocbl
-
cobalamin-dependent
- propionyl-coa
-
adenosylcobalamin-dependent
- drug development
- isobutyryl-coa
-
cofactor-dependent
- shermanii
-
cytodifferentiation
- methylcobalamin
- phosphoenzyme
-
cobiialamin
- analysis
- medicine
- synthesis
Reaction
Synonyms
AfUGM, ANIA_03112, CdUGM, galactopyranose mutase, Glf, GLF gene product, GLF-1, glfA, MtUGM, mutase, Mutase, uridine diphosphogalactopyranose, TcUGM, UDP galactopyranose mutase, UDP-D-galactopyranose mutase, UDP-Gal mutase, UDP-galactopyranose mutase, UDP-Galp mutase, UGM, UgmA, UNGM, uridine 5'-diphosphate galactopyranose mutase, uridine 5'-diphosphate galactopyranosemutase, uridine 5'-diphosphate-galactopyranose mutase, uridine diphosphate galactopyranose mutase
ECTree
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KM Value
KM Value on EC 5.4.99.9 - UDP-galactopyranose mutase
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0.023
UDP-2,3-dideoxy-2,2,3,3-tetrafluoro-alpha-D-galactopyranose
pH 7.5, 37°C, recombinant enzyme
1.14
UDP-2-amino-2-deoxy-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.203
UDP-2-deoxy-2-fluoro-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.28
UDP-3-deoxy-3-fluoro-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.2
UDP-6-deoxy-6-fluoro-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
3.15
UDP-6-deoxy-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.032
pH and temperature not specified in the publication, recombinant mutant Y100A
0.057
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant Y104A
0.078
UDP-alpha-D-galactofuranose
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pH and temperature not specified in the publication, recombinant wild-type enzyme
0.11
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant wild-type enzyme
0.14
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant wild-type enzyme
0.166
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant N207A
0.193
UDP-alpha-D-galactofuranose
pH 7.0, 37°C, recombinant mutant W315A
0.334
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant Y317A
0.38
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant Y317A
0.45
UDP-alpha-D-galactofuranose
pH 7.0, 37°C, recombinant wild-type enzyme
0.478
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant Q103A
2.153
UDP-alpha-D-galactofuranose
pH and temperature not specified in the publication, recombinant mutant Q107A
0.0425
UDP-alpha-D-galactopyranose
pH 7.0, 37°C, wild-type enzyme
0.094
pH 7.0, 37°C, recombinant wild-type enzyme
0.7
UDP-beta-L-arabinofuranose
pH 7.0, 37°C, recombinant mutant W315A
0.016
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.022
UDP-D-galactofuranose
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37°C, pH 7.5, in presence of 20 mM sodium dithionite
0.087
UDP-D-galactofuranose
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in 25 mM HEPES, 125 mM NaCl, 20 mM dithionite, pH 7.5, at 37°C
0.11
UDP-D-galactofuranose
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in 25 mM HEPES, 125 mM NaCl, 20 mM dithionite, pH 7.5, at 37°C
0.805
UDP-D-galactopyranose
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in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C
0.055
UDP-galactopyranose
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wild type enzyme, in 50 mM sodium phosphate buffer pH 7.0
additional information
steady-state kinetics of wild-type and mutant enzymes, overview
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additional information
additional information
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steady-state kinetics of wild-type and mutant enzymes, overview
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additional information
additional information
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high-affinity binding to the enzyme is only obtained with the chromophore 5-carboxytetramethylrhodamine, i.e. TAMRA, linked to UDP by either 2 or 6 carbons, 6times less when UDP is linked to fluorescein, kinetics, overview
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additional information
additional information
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Michaelis-Menten kinetics of wild-type and mutant enzymes
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additional information
additional information
Michaelis-Menten kinetics and kinetic solvent viscosity effects with wild-type and mutant enzymes. A strong dependence of the kcat value on solution viscosity is observed when UDP-beta-L-arabinofuranose is used as the substrate with the wild-type enzyme
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additional information
additional information
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Michaelis-Menten kinetics and kinetic solvent viscosity effects with wild-type and mutant enzymes. A strong dependence of the kcat value on solution viscosity is observed when UDP-beta-L-arabinofuranose is used as the substrate with the wild-type enzyme
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