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5.4.99.7: Lanosterol synthase

This is an abbreviated version!
For detailed information about Lanosterol synthase, go to the full flat file.

Word Map on EC 5.4.99.7

Reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene
=
lanosterol

Synonyms

2,3 oxidosqualene:lanosterol cyclase, 2,3-Epoxysqualene lanosterol-cyclase, 2,3-epoxysqualene--lanosterol cyclase, 2,3-Epoxysqualene-lanosterol cyclase, 2,3-Oxidosqualene cyclase, 2,3-oxidosqualene cyclase-lanosterol synthase, 2,3-Oxidosqualene sterol cyclase, 2,3-Oxidosqualene-lanosterol cyclase, 2,3-oxidosqualene:lanosterol cyclase, AtLAS, Cyclase, 2,3-oxidosqualene-lanosterol, ERG7, Erg7p, hOSC, Lanosterol 2,3-oxidosqualene cyclase, lanosterol synthase, LAS, LAS1, Lss, OSC, OSLC, Oxidosqualene cyclase, oxidosqualene cyclase/lanosterol synthase, Oxidosqualene--lanosterol cyclase, Oxidosqualene-lanosterol cyclase, oxidosqualene:lanosterol cyclase, SceOSC, Squalene 2,3-epoxide:lanosterol cyclase, Squalene 2,3-oxide-lanosterol cyclase, Squalene epoxidase-cyclase, Squalene-2,3-oxide-lanosterol cyclase, tuber-specific StLAS-like

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.7 Lanosterol synthase

Specific Activity

Specific Activity on EC 5.4.99.7 - Lanosterol synthase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0000015
0.0000025
-
mutant C457/E526C at 35°C
0.0000048
-
mutant C457/E526A at 35°C
0.0000063
-
mutant C457 at 25°C
0.0000087
-
mutant C457/E526D at 25°C
0.0000097
-
mutant C457/E526Q at 25°C
0.0000113
-
mutant C457/E525C at 25°C
0.0000128
-
mutant C457/E526D at 35°C
0.0000172
-
wild-type, at 25°C
0.0000192
-
mutant C457/E526Q at 35°C
0.000021
-
mutant C457/E525C at 35°C
0.0000213
-
mutant C457 at 35°C
0.0000292
-
wild-type, at 35°C
0.0000429
cataractous Shumiya cataract rat
0.000046
normal Shumiya cataract rat
0.0043
-
-
1.747
-
-
additional information