5.4.99.7: Lanosterol synthase

This is an abbreviated version!
For detailed information about Lanosterol synthase, go to the full flat file.

Word Map on EC 5.4.99.7

5.4.99.7

anatomical

subtypes

omnibus

metastasis

adenocarcinoma

kaplan-meier

univariate

download

posterior

lncrnas

neck

clinicopathological

anatomy

high-risk

tumorigenesis

worse

tomography

encyclopedia

glioblastoma

low-risk

registration

immunotherapy

glioma

kyoto

manual

automat

nomogram

lasso

checkpoint

arch

fracture

spine

immune-related

radiograph

transverse

disease-free

occipital

cernas

probabilistic

hnscc

neuroimaging

ccrcc

vertebra

stereotactic

skull

tumor-infiltrating

tensor

sagittal

screw

c-index

medicine

synthesis

drug development

nutrition

Reaction

Synonyms

2,3 oxidosqualene:lanosterol cyclase, 2,3-Epoxysqualene lanosterol-cyclase, 2,3-epoxysqualene--lanosterol cyclase, 2,3-Epoxysqualene-lanosterol cyclase, 2,3-Oxidosqualene cyclase, 2,3-oxidosqualene cyclase-lanosterol synthase, 2,3-Oxidosqualene sterol cyclase, 2,3-Oxidosqualene-lanosterol cyclase, 2,3-oxidosqualene:lanosterol cyclase, AtLAS, Cyclase, 2,3-oxidosqualene-lanosterol, ERG7, Erg7p, hOSC, Lanosterol 2,3-oxidosqualene cyclase, lanosterol synthase, LAS, LAS1, Lss, OSC, OSLC, Oxidosqualene cyclase, oxidosqualene cyclase/lanosterol synthase, Oxidosqualene--lanosterol cyclase, Oxidosqualene-lanosterol cyclase, oxidosqualene:lanosterol cyclase, SceOSC, Squalene 2,3-epoxide:lanosterol cyclase, Squalene 2,3-oxide-lanosterol cyclase, Squalene epoxidase-cyclase, Squalene-2,3-oxide-lanosterol cyclase, tuber-specific StLAS-like

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.99 Transferring other groups

5.4.99.7 Lanosterol synthase

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Results	in table
9	Activating Compound
136	AA Sequence
13	Application
1	CAS Registry Number
29	Cloned(Commentary)
5	Crystallization (Commentary)
59091	Disease/ Diagnostics
2	Expression
15	General Information
2	General Stability
173	IC50 Value
345	Inhibitors
31	Ki Value [mM]
7	KM Value [mM]
35	Localization
1	Metals/Ions
19	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
127	Organism
6	Pathway
2	PDB ID
3	pH Optimum
1	pH Range
1	pI Value
1	Posttranslational Modification
166	Protein Variants
17	Purification (Commentary)
4	Reaction
3	Reaction Type
127	Reference
58	Source Tissue
24	Specific Activity [micromol/min/mg]
6	Storage Stability
138	Substrates and Products (Substrate)
15	Subunits
135	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]

KI Value

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KI Value on EC 5.4.99.7 - Lanosterol synthase

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0.000013

27-norsqualene

Sus scrofa

pH 7.4, 37°C, liver microsomes

727324

0.00002

28-noroxidosqualene

Sus scrofa

pH 7.4, 37°C, liver microsomes

727324

0.000015

29-norsqualene

Sus scrofa

pH 7.4, 37°C, liver microsomes

727324

0.00112 - 0.00342

7-(4-allylmethylamino-but-2-ynyloxy)chromen-2-one

2 entries

0.07876 - 0.1028

7-(morpholinyl-N-hexyloxy)chromen-2-one

3 entries

0.00535 - 0.1024

7-(morpholinyl-N-octanyloxy)chromen-2-one

3 entries

0.00248 - 0.03154

7-(piperidinyl-N-hexyloxy)chromen-2-one

2 entries

0.00018 - 0.00414

7-[10-(allylmethylamino)-decyloxy]chromen-2-one

3 entries

0.00185 - 0.07266

7-[4'-(N-diethylamino)-but-2-ynyloxy]chromen-2-one

3 entries

0.00052 - 0.1063

7-[4'-(N-pyrrolidyn)-but-2-ynyloxy]chromen-2-one

3 entries

0.00015 - 0.00406

7-[6-(allylmethylamino)-hexyloxy]-chromen-2-one

3 entries

0.00104 - 0.02543

7-[8'(dimethylamino-N-octyloxy)]chromen-2-one

3 entries

0.008

S23515

Rattus norvegicus

661036

additional information

7-(4-allylmethylamino-but-2-ynyloxy)chromen-2-one

2 entries