Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

5.4.99.64: 2-hydroxyisobutanoyl-CoA mutase

This is an abbreviated version!
For detailed information about 2-hydroxyisobutanoyl-CoA mutase, go to the full flat file.

Word Map on EC 5.4.99.64

Reaction

2-hydroxy-2-methylpropanoyl-CoA
=
(S)-3-hydroxybutanoyl-CoA

Synonyms

2-hydroxyisobutyryl-CoA mutase, Btus_0469, Btus_0470, EC 5.3.3.20, HCM, HcmA, hcmAB, HcmB, RcmA, RcmB

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.64 2-hydroxyisobutanoyl-CoA mutase

Reference

Reference on EC 5.4.99.64 - 2-hydroxyisobutanoyl-CoA mutase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yaneva, N.; Schuster, J.; Schafer, F.; Lede, V.; Przybylski, D.; Paproth, T.; Harms, H.; Muller, R.H.; Rohwerder, T.
Bacterial acyl-CoA mutase specifically catalyzes coenzyme B12-dependent isomerization of 2-hydroxyisobutyryl-CoA and (S)-3-hydroxybutyryl-CoA
J. Biol. Chem.
287
15502-15511
2012
Aquincola tertiaricarbonis (I3VE77 and I3VE74), Aquincola tertiaricarbonis, Aquincola tertiaricarbonis L108 (I3VE77 and I3VE74)
Manually annotated by BRENDA team
Weichler, M.T.; Kurteva-Yaneva, N.; Przybylski, D.; Schuster, J.; Mueller, R.H.; Harms, H.; Rohwerder, T.
Thermophilic coenzyme B12-dependent acyl coenzyme A (CoA) mutase from Kyrpidia tusciae DSM 2912 preferentially catalyzes isomerization of (R)-3-hydroxybutyryl-CoA and 2-hydroxyisobutyryl-CoA
Appl. Environ. Microbiol.
81
4564-4572
2015
Kyrpidia tusciae DSM 2912 (D5WTR7 and D5WTR8), Kyrpidia tusciae DSM 2912
Manually annotated by BRENDA team
Przybylski, D.; Rohwerder, T.; Harms, H.; Yaneva, N.; Mueller, R.H.
Synthesis of the building block 2-hydroxyisobutyrate from fructose and butyrate by Cupriavidus necator H16
Appl. Microbiol. Biotechnol.
97
8875-8885
2013
Aquincola tertiaricarbonis (I3VE77 and I3VE74), Aquincola tertiaricarbonis L108 (I3VE77 and I3VE74)
Manually annotated by BRENDA team
Kurteva-Yaneva, N.; Zahn, M.; Weichler, M.T.; Starke, R.; Harms, H.; Muller, R.H.; Strater, N.; Rohwerder, T.
Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase
J. Biol. Chem.
290
9727-9737
2015
Aquincola tertiaricarbonis (I3VE77 and I3VE74), Aquincola tertiaricarbonis
Manually annotated by BRENDA team