5.4.99.64: 2-hydroxyisobutanoyl-CoA mutase
This is an abbreviated version!
For detailed information about 2-hydroxyisobutanoyl-CoA mutase, go to the full flat file.
Word Map on EC 5.4.99.64
-
5.4.99.64
-
b12-dependent
-
aquincola
-
tertiaricarbonis
-
acyl-coa
-
s-3-hydroxybutyryl-coa
-
2-hydroxyisobutyric
-
chaperone
-
mutases
-
2-hydroxyisobutyrylation
-
isomerization
-
isovaleryl-coa
-
tert-butyl
-
thioester
-
synthesis
- 5.4.99.64
-
b12-dependent
-
aquincola
- tertiaricarbonis
- acyl-coa
-
s-3-hydroxybutyryl-coa
-
2-hydroxyisobutyric
- chaperone
- mutases
-
2-hydroxyisobutyrylation
-
isomerization
- isovaleryl-coa
-
tert-butyl
- thioester
- synthesis
Reaction
Synonyms
2-hydroxyisobutyryl-CoA mutase, Btus_0469, Btus_0470, EC 5.3.3.20, HCM, HcmA, hcmAB, HcmB, RcmA, RcmB
ECTree
5.4.99.64 2-hydroxyisobutanoyl-CoA mutaseAdvanced search results
results (
results (KM Value
KM Value on EC 5.4.99.64 - 2-hydroxyisobutanoyl-CoA mutase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.55
isobutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.0075
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
0.008
(R)-3-hydroxybutanoyl-CoA
mutant D117A, pH 6.6, 30°C
0.067
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.067
(R)-3-hydroxybutanoyl-CoA
mutant D117V, pH 6.6, 30°C
0.298
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.298
(R)-3-hydroxybutanoyl-CoA
mutant I90A, pH 6.6, 30°C
1.66
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
1.66
(R)-3-hydroxybutanoyl-CoA
wild-type, pH 6.6, 30°C
0.0146
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
0.015
(S)-3-hydroxybutanoyl-CoA
mutant D117A, pH 6.6, 30°C
0.117
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.117
(S)-3-hydroxybutanoyl-CoA
mutant D117V, pH 6.6, 30°C
0.128
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.128
(S)-3-hydroxybutanoyl-CoA
wild-type, pH 6.6, 30°C
0.433
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme, I90A (mutation in subunit HcmA)
0.433
(S)-3-hydroxybutanoyl-CoA
mutant I90A, pH 6.6, 30°C
0.663
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90L (mutation in subunit HcmA)
0.663
(S)-3-hydroxybutanoyl-CoA
mutant I90L, pH 6.6, 30°C
1.76
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V
1.76
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
1.76
(S)-3-hydroxybutanoyl-CoA
mutant I90V, pH 6.6, 30°C
0.0435
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.235
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.374
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.977
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
0.042
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
0.042
2-hydroxy-2-methylpropanoyl-CoA
mutant D117A, pH 6.6, 30°C
0.061
2-hydroxy-2-methylpropanoyl-CoA
mutant D117V, pH 6.6, 30°C
0.0614
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.104
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.104
2-hydroxy-2-methylpropanoyl-CoA
-
pH 6.6, 30°C, wild-type enzyme
0.104
2-hydroxy-2-methylpropanoyl-CoA
wild-type, pH 6.6, 30°C
0.304
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.304
2-hydroxy-2-methylpropanoyl-CoA
mutant I90A, pH 6.6, 30°C
0.517
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90L (mutation in subunit HcmA)
0.517
2-hydroxy-2-methylpropanoyl-CoA
mutant I90L, pH 6.6, 30°C
1.84
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V
1.84
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
1.84
2-hydroxy-2-methylpropanoyl-CoA
mutant I90V, pH 6.6, 30°C
0.147
isovaleryl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.288
isovaleryl-CoA
pH 6.6, 30°C, wild-type enzyme
0.329
isovaleryl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
