5.4.99.64: 2-hydroxyisobutanoyl-CoA mutase
This is an abbreviated version!
For detailed information about 2-hydroxyisobutanoyl-CoA mutase, go to the full flat file.
Word Map on EC 5.4.99.64
-
5.4.99.64
-
b12-dependent
-
aquincola
-
tertiaricarbonis
-
acyl-coa
-
s-3-hydroxybutyryl-coa
-
2-hydroxyisobutyric
-
chaperone
-
mutases
-
2-hydroxyisobutyrylation
-
isomerization
-
isovaleryl-coa
-
tert-butyl
-
thioester
-
synthesis
- 5.4.99.64
-
b12-dependent
-
aquincola
- tertiaricarbonis
- acyl-coa
-
s-3-hydroxybutyryl-coa
-
2-hydroxyisobutyric
- chaperone
- mutases
-
2-hydroxyisobutyrylation
-
isomerization
- isovaleryl-coa
-
tert-butyl
- thioester
- synthesis
Reaction
Synonyms
2-hydroxyisobutyryl-CoA mutase, Btus_0469, Btus_0470, EC 5.3.3.20, HCM, HcmA, hcmAB, HcmB, RcmA, RcmB
ECTree
5.4.99.64 2-hydroxyisobutanoyl-CoA mutaseAdvanced search results
results (
results (KCat KM Value
KCat KM Value on EC 5.4.99.64 - 2-hydroxyisobutanoyl-CoA mutase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
kcat/KM VALUE [1/mMs-1] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0018
isobutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.00199
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.002
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.002
(R)-3-hydroxybutanoyl-CoA
wild-type, pH 6.6, 30°C
0.012
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.012
(R)-3-hydroxybutanoyl-CoA
mutant I90A, pH 6.6, 30°C
2.583
(R)-3-hydroxybutanoyl-CoA
mutant D117V, pH 6.6, 30°C
2.6
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
3.667
(R)-3-hydroxybutanoyl-CoA
mutant D117A, pH 6.6, 30°C
3.7
(R)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
0.0047
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme, I90A (mutation in subunit HcmA)
0.005
(S)-3-hydroxybutanoyl-CoA
mutant I90A, pH 6.6, 30°C
0.005
(S)-3-hydroxybutanoyl-CoA
mutant I90L, pH 6.6, 30°C
0.0052
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90L (mutation in subunit HcmA)
0.018
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
0.018
(S)-3-hydroxybutanoyl-CoA
mutant I90V, pH 6.6, 30°C
0.019
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V
0.525
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.525
(S)-3-hydroxybutanoyl-CoA
mutant D117V, pH 6.6, 30°C
1.5
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
1.5
(S)-3-hydroxybutanoyl-CoA
wild-type, pH 6.6, 30°C
1.56
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
1.75
(S)-3-hydroxybutanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
1.75
(S)-3-hydroxybutanoyl-CoA
mutant D117A, pH 6.6, 30°C
0.017
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
0.043
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.057
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
3.2
2,2-dimethylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.011
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V
0.012
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
0.012
2-hydroxy-2-methylpropanoyl-CoA
mutant I90V, pH 6.6, 30°C
0.013
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90L (mutation in subunit HcmA)
0.013
2-hydroxy-2-methylpropanoyl-CoA
mutant I90L, pH 6.6, 30°C
0.082
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme I90A (mutation in subunit HcmA)
0.082
2-hydroxy-2-methylpropanoyl-CoA
mutant I90A, pH 6.6, 30°C
0.48
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, wild-type enzyme
0.48
2-hydroxy-2-methylpropanoyl-CoA
-
pH 6.6, 30°C, wild-type enzyme
0.48
2-hydroxy-2-methylpropanoyl-CoA
wild-type, pH 6.6, 30°C
0.727
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
0.727
2-hydroxy-2-methylpropanoyl-CoA
mutant D117V, pH 6.6, 30°C
1.05
2-hydroxy-2-methylpropanoyl-CoA
pH 6.6, 30°C, mutant enzyme D117A (mutation in subunit HcmA)
1.053
2-hydroxy-2-methylpropanoyl-CoA
mutant D117A, pH 6.6, 30°C
0.028
isovaleryl-CoA
pH 6.6, 30°C, mutant enzyme I90V (mutation in subunit HcmA)
0.062
isovaleryl-CoA
pH 6.6, 30°C, mutant enzyme D117V (mutation in subunit HcmA)
