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5.4.99.63: ethylmalonyl-CoA mutase

This is an abbreviated version!
For detailed information about ethylmalonyl-CoA mutase, go to the full flat file.

Word Map on EC 5.4.99.63

Reaction

(2R)-ethylmalonyl-CoA
=
(2S)-methylsuccinyl-CoA

Synonyms

Ecm, ethylmalonyl coenzyme A mutase, ethylmalonyl-CoA mutase, meaA

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.63 ethylmalonyl-CoA mutase

Purification

Purification on EC 5.4.99.63 - ethylmalonyl-CoA mutase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant enzyme from Escherichia coli
recombinant enzyme. Purified recombinant Ecm is unable to form methylsuccinyl-CoA from ethylmalonyl-CoA when ethylmalonyl-CoA is produced by reductive carboxylation of crotonyl-CoA carboxylase/reductase. Addition of cell extract of the gene insertion mutant ecm::kan to the enzyme assay restores ethylmalonyl-CoA mutase activity