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5.4.99.50: friedelin synthase

This is an abbreviated version!
For detailed information about friedelin synthase, go to the full flat file.

Word Map on EC 5.4.99.50

Reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene
=
friedelin

Synonyms

FRS, FRS2, FRS3, MiFRS, MiFRS2, MiFRS3, OSC

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.50 friedelin synthase

Reference

topprint

Reference on EC 5.4.99.50 - friedelin synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wang, Z.; Yeats, T.; Han, H.; Jetter, R.
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids
J. Biol. Chem.
285
29703-29712
2010
Kalanchoe daigremontiana
Manually annotated by BRENDA team
Alves, T.B.; Souza-Moreira, T.M.; Valentini, S.R.; Zanelli, C.F.; Furlan, M.
Friedelin in Maytenus ilicifolia is produced by friedelin synthase isoforms
Molecules
23
700-711
2018
Monteverdia ilicifolia (A0A1L3HE30), Monteverdia ilicifolia (A0A2R3ZF24), Monteverdia ilicifolia (A0A2R3ZF26), Monteverdia ilicifolia (A0A2R3ZF31), Monteverdia ilicifolia
Manually annotated by BRENDA team
Souza-Moreira, T.M.; Alves, T.B.; Pinheiro, K.A.; Felippe, L.G.; De Lima, G.M.; Watanabe, T.F.; Barbosa, C.C.; Santos, V.A.; Lopes, N.P.; Valentini, S.R.; Guido, R.V.; Furlan, M.; Zanelli, C.F.
Friedelin synthase from Maytenus ilicifolia leucine 482 plays an essential role in the production of the most rearranged pentacyclic triterpene
Sci. Rep.
6
36858
2016
Monteverdia ilicifolia (A0A1L3HE30), Monteverdia ilicifolia
Manually annotated by BRENDA team