5.4.99.5: chorismate mutase
This is an abbreviated version!
For detailed information about chorismate mutase, go to the full flat file.
Word Map on EC 5.4.99.5
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5.4.99.5
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shikimate
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sieve
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monofunctional
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phloem
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l-phenylalanine
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l-tyrosine
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7-phosphate
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mutases
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t-proteins
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3-deoxy-d-arabino-heptulosonate
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phenylpyruvate
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claisen
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arogenate
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pericyclic
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nonketotic
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hyperglycinemia
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isochorismate
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cyclohexadienyl
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hydroxyphenylpyruvate
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photorespiratory
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preorganization
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drug development
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3-deoxy-d-arabino-heptulosonate-7-phosphate
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meloidogyne
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synthesis
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agriculture
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analysis
- 5.4.99.5
- shikimate
-
sieve
-
monofunctional
- phloem
- l-phenylalanine
- l-tyrosine
- 7-phosphate
- mutases
-
t-proteins
-
3-deoxy-d-arabino-heptulosonate
- phenylpyruvate
-
claisen
- arogenate
-
pericyclic
-
nonketotic
- hyperglycinemia
- isochorismate
-
cyclohexadienyl
- hydroxyphenylpyruvate
-
photorespiratory
-
preorganization
- drug development
-
3-deoxy-d-arabino-heptulosonate-7-phosphate
- meloidogyne
- synthesis
- agriculture
- analysis
Reaction
Synonyms
105-MtCM, 90-MtCM, AmtCM1, AmtCM2, aro7, AroA, AroH, AroQ, AtCM1, AtCM2, AtCM3, Bacillus subtilis chorismate mutase, Bphy_7813, BsAroH, BsCM, BsCM_2, BTH_I1596, chorismate mutase, chorismate mutase 1, chorismate mutase-prephenate dehydrogenase, Chorismate mutase/prephenate dehydratase, CM, CM type 2, CM-1, CM-prephenate dehydratase, CM-TyrAp, CM/PDT, CM/PDT/PDHG, CM0819, CM1, CM2, EcCM, EcCM-R, MI-CM-1, MI-CM-2, MjCM, MTB chorismate mutase, MTB CM, MtbCM, MtCM, Mutase, chorismate, Mycobacterium tuberculosis chorismate mutase, Mycobacterium tuberculosis H37Rv chorismate mutase, NC30, P protein, P-protein, PheA, PpCM1, PpCM2, Rv0948c, Rv1885c, SmCM, Tparo7, TtCM, y2828, YCM
ECTree
5.4.99.5 chorismate mutaseAdvanced search results
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results (KI Value
KI Value on EC 5.4.99.5 - chorismate mutase
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Ki VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.00032 - 0.0076
(1S,3R,5R)-1-hydroxy-5-nitro-2-oxabicyclo[3.3.1]non-6-ene-3-carboxylic acid
0.23
(1S,3S,5R)-1-hydroxy-5-nitro-2-oxabicyclo[3.3.1]non-6-ene-3-carboxylic acid
-
30°C, pH 7.5, wild-type
0.01771
(2Z)-2-(4-chlorophenyl)-3-(4,5-dimethoxy-2-nitrophenyl)prop-2-enoic acid
-
0.0211
(2Z)-2-(4-chlorophenyl)-3-[4-(dimethoxymethyl)-2-nitrophenyl]prop-2-enoic acid
pH 7.0, 37°C
0.0177
2-[2-[3-(tert-butoxycarbonyl)-2-phenyl-1,3-thiazolidin-4-yl]ethyl]-4-methylpentanoic acid
pH 7.0, 37°C
0.0057
3-((dihydroxyamino)thio)-4-((3,5-dimethoxyphenethyl)amino)-5-nitrobenzoic acid
pH 7.0, 37°C
0.0057
4-(3,4-dimethoxyphenethylamino)-3-nitro-5-sulfamoylbenzoic acid
pH and temperature not specified in the publication
0.0057
4-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-nitro-5-sulfamoylbenzoic acid
4-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-nitro-5-sulfamoylbenzoic acid shows the most potent inhibition with Ki value of 0.0057 mM against MtCM
0.0037
8-hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid
-
-
0.0211
N-[[3-(tert-butoxycarbonyl)-2-phenyl-1,3-thiazolidin-4-yl]carbonyl]leucine
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0.001
(1R,3R,5S)-3-carboxy-1-hydroxy-2-oxabicyclo[3.3.1]non-6-ene-5-carboxylate
-
30°C, pH 7.5, wild-type
0.0023
(1R,3R,5S)-3-carboxy-1-hydroxy-2-oxabicyclo[3.3.1]non-6-ene-5-carboxylate
-
30°C, pH 7.5, chorismate mutase domain of P-protein
0.051
(1R,3R,5S)-3-carboxy-1-hydroxy-2-oxabicyclo[3.3.1]non-6-ene-5-carboxylate
-
30°C, pH 7.5, mutant DELTA117-127
0.00032
(1S,3R,5R)-1-hydroxy-5-nitro-2-oxabicyclo[3.3.1]non-6-ene-3-carboxylic acid
-
30°C, pH 7.5, wild-type
0.0029
(1S,3R,5R)-1-hydroxy-5-nitro-2-oxabicyclo[3.3.1]non-6-ene-3-carboxylic acid
-
30°C, pH 7.5, mutant DELTA117-127
0.0076
(1S,3R,5R)-1-hydroxy-5-nitro-2-oxabicyclo[3.3.1]non-6-ene-3-carboxylic acid
-
30°C, pH 7.5, chorismate mutase domain of P-protein
additional information
oxabicyclic dicarboxylic acid
>> 1 mM mutant C88S/R90K
additional information
oxabicyclic dicarboxylic acid
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>> 1 mM mutant C88S/R90K
