5.4.99.39: beta-amyrin synthase

This is an abbreviated version!
For detailed information about beta-amyrin synthase, go to the full flat file.

Reaction

Synonyms

AMS1, amyrin synthase, B-AS, bAS, BAS-like 2, BAS1, BAS2, beta-amyrin cyclase, beta-amyrin synthase, beta-AS, betaAS, BPY, CbbAS, CrAS, EsBAS, EtAS, GmAMS1, GsAS1, GsAS2, MdOSC1, MtAMY1, multifunctional OSC, ObAS1, OPSC 1, OSC, OSC1, OSC2, OXA1, Oxidosqualene cyclase, PBA, PlgOSC1, PNY, PSY, PtBS, SITTS1, SlTTS1, SvBS

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.99 Transferring other groups

                5.4.99.39 beta-amyrin synthase

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Results	in table
1	Activating Compound
57	AA Sequence
2	Application
44	Cloned(Commentary)
12	Expression
65	General Information
6	IC50 Value
6	Inhibitors
3	kcat/KM [mM/s]
3	Ki Value [mM]
4	KM Value [mM]
4	Localization
7	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
60	Organism
11	Pathway
2	pH Optimum
11	pI Value
74	Protein Variants
3	Purification (Commentary)
7	Reaction
57	Reference
79	Source Tissue
1	Specific Activity [micromol/min/mg]
64	Substrates and Products (Substrate)
19	Subunits
70	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
3	Turnover Number [1/s]

Expression

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Expression on EC 5.4.99.39 - beta-amyrin synthase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

after 24 h of elicitation, beta-amyrin synthase transcripts are increased at 0.1, 1, and 2 mM of methyl jasmonate, and they are increased at 0.1 and 1 mM salicylic acid

Glycyrrhiza glabra

Q9MB42

716908

CrAS is preferentially expressed in leaf epidermis, in younger leaves and during the earlier stages of seedling development in Catharanthus roseus

Catharanthus roseus

-

730571

GsAS1 transcription is 9.8fold induced by methyl jasmonate (MeJA) treatment with increased oleanolic acid content, while salicylic acid has no effect

Gentiana straminea

A0A023U990, C1K2M2

749323

GsAS2 transcription is 12.2fold induced by methyl jasmonate (MeJA) treatment with increased oleanolic acid content, while salicylic acid has no effect

Gentiana straminea

A0A023U990, C1K2M2

749323

highest expression in roots

Polygala tenuifolia

-

730595

RNAi-directed suppression of GsAS1 in Gentiana straminea decreases oleonolic acid levels by 65.9%

Gentiana straminea

A0A023U990, C1K2M2

749323

RNAi-directed suppression of GsAS2 in Gentiana straminea decreases oleonolic acid levels by 21.0%

Gentiana straminea

A0A023U990, C1K2M2

749323

the enzyme is induced by methyl jasmonate (MeJA). The transcription of EsBAS is clearly enhanced at 12 and 24 h after MeJA treatment and reduced to the level of the control (without MeJA treatment) at 72 h after MeJA treatment

Eleutherococcus senticosus

A0A1P8W708

746004

the enzyme is inducible by methyl jasmonate by 50fold in cell suspension cultures

Medicago truncatula

-

748823

the transcription of gene CbbAS is upregulated 4-24 h after treatment of seedlings with methyl jasmonate

Eschenbachia blinii

A0A2P0VE73

747786

the treatment with 0.1 mM methyl jasmonate yields greater accumulation of beta-amyrin as well as B-AS activity

2 entries

the treatment with 0.1 mM methyl jasmonate yields greater accumulation of beta-amyrin as well as B-AS activity

Medicago truncatula

-

716192

the treatment with 0.1 mM methyl jasmonate yields greater accumulation of beta-amyrin as well as B-AS activity

Gentiana straminea

-

716192