5.4.99.28: tRNA pseudouridine32 synthase
This is an abbreviated version!
For detailed information about tRNA pseudouridine32 synthase, go to the full flat file.
Word Map on EC 5.4.99.28
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5.4.99.28
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synthases
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rrna
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dual-specificity
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pseudouridylating
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5-fluorouridine
- 5.4.99.28
- synthases
- rrna
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dual-specificity
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pseudouridylating
- 5-fluorouridine
Reaction
Synonyms
pseudouridine synthase RluA, Pus9, Rib2/Pus8p, RluA, tRNA:Psi32-synthase
ECTree
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Substrates Products
Substrates Products on EC 5.4.99.28 - tRNA pseudouridine32 synthase
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REACTION DIAGRAM
tRNA uridine32
tRNA pseudouridine32
RluA is the only synthase for formation of pseudouridine746 in 23S tRNA
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tRNA uridine32
tRNA pseudouridine32
stem-loop RNAs are good substrates for RluA
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tRNA uridine32
tRNA pseudouridine32
substrate tRNAPhe. The enzyme is also responsible for the formation of pseudouridine746 in 23S rRNA
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tRNA uridine32
tRNA pseudouridine32
substrate: Escherichia coli tRNAPhe
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tRNA uridine32
tRNA pseudouridine32
Rib2/Pus8p acts specifically on cytoplasmic tRNAs, whereas Pus9p modifies the same position mostly in mitochondrial tRNAs
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