5.4.99.22: 23S rRNA pseudouridine2605 synthase
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For detailed information about 23S rRNA pseudouridine2605 synthase, go to the full flat file.
Reaction
Synonyms
RluB, YciL
ECTree
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General Information
General Information on EC 5.4.99.22 - 23S rRNA pseudouridine2605 synthase
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malfunction
physiological function
RluB is associated with a particle that migrates slightly slower than the 50S ribosomal subunit, suggesting that it acts during 50S subunit maturation
deletion of rluB leads to accumulation of free 30S and 50S ribosomal subunits. Growth of an rluB deletion mutant is impaired in the cold
malfunction
no formation of pseudouridine2605 in 23S rRNA of an rluB null mutant. An rluB null mutant or an rluB rluF double null mutant exhibits no obvious growth defect