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5.4.99.17: squalene-hopene cyclase

This is an abbreviated version!
For detailed information about squalene-hopene cyclase, go to the full flat file.

Word Map on EC 5.4.99.17

Reaction

squalene
+
H2O
=
hopan-22-ol

Synonyms

AacSHC, cyclase, squalene-hopanoid, SHC, SHC1, SHC2, Spterp25, SQ-hopene cyclase, squalene hopene cyclase, squalene-hopene cyclase, ZmoSHC1, ZmSHC1

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.17 squalene-hopene cyclase

Crystallization

Crystallization on EC 5.4.99.17 - squalene-hopene cyclase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
cocrystallization with 2-azasqualene
-
complexes with 11 human oxidosqualene cyclase inhibitors produced by cocrystallization, elucidation of the structures by X-ray diffraction analyses
resolution of 2.0 Angstrom