5.4.99.12: tRNA pseudouridine38-40 synthase
This is an abbreviated version!
For detailed information about tRNA pseudouridine38-40 synthase, go to the full flat file.
Reaction
Synonyms
Deg1, Deg1p, hisT, mPus3p, pseudouridine synthase, pseudouridine synthase 3, pseudouridine synthase I, PSUI, PUS3, Pus3p, tRNA pseudouridine synthase 3, tRNA pseudouridine synthase I, TruA
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Reference on EC 5.4.99.12 - tRNA pseudouridine38-40 synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Marvel, C.C.; Arps, P.J.; Rubin, B.C.; Kammen, H.O.; Penhoet, E.E.; Winkler, M.E.
HisT is part of a multigene operon in Escherichia coli K-12
J. Bacteriol.
161
60-71
1985
Escherichia coli K-12
Green, C.; Kammen, H.; Penhoet, E.
Purification and properties of a mammalian tRNA pseudouridine synthase
J. Biol. Chem.
257
3045-3052
1982
Bos taurus
Kammen, H.; Marvel, C.; Hardy, L.; Penhoet, E.
Purification structure and properties of Escherichia coli tRNA pseudouridine synthase I
J. Biol. Chem.
263
2255-2263
1988
Escherichia coli
Chihade, J.; Horne, D.
Single nucleotide modulation of uridine to pseudouridine rearrangement in transfer RNA catalyzed by pseudouridine synthase I
J. Mol. Recognit.
9
524-527
1996
Escherichia coli
Lecointe, F.; Simos, G.; Sauer, A.; Hurt, E.; Motorin, Y.; Grosjean, H.
Characterization of yeast protein Deg1 as pseudouridine synthase (pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop
J. Biol. Chem.
273
1316-1323
1998
Saccharomyces cerevisiae (P31115), Saccharomyces cerevisiae
Foster, P.G.; Huang, L.; Santi, D.; Stroud, R.
The structural basis of tRNA recognition and pseudouridine formation by pseudouridine synthase I
Nat. Struct. Biol.
7
23-27
2000
Escherichia coli
Lecointe, F.; Namy, O.; Hatin, I.; Simos, G.; Rousset, J-P.; Grosjean, H.
Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency
J. Biol. Chem.
277
30445-30453
2002
Saccharomyces cerevisiae (P31115), Saccharomyces cerevisiae
Chen, J.; Patton, J.R.
Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA
Biochemistry
39
12723-12730
2000
Mus musculus (Q9JI38), Mus musculus
Gu, X.; Liu, Y.; Santi, D.V.
The mechanism of pseudouridine synthase I as deduced from its interaction with 5-fluorouracil-tRNA
Proc. Natl. Acad. Sci. USA
96
14270-14275
1999
Saccharomyces cerevisiae, Escherichia coli (P07649)
Hur, S.; Stroud, R.M.
How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA
Mol. Cell
26
189-203
2007
Escherichia coli, Escherichia coli (P07649)
Dong, X.; Bessho, Y.; Shibata, R.; Nishimoto, M.; Shirouzu, M.; Kuramitsu, S.; Yokoyama, S.
Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8
RNA Biol.
3
115-122
2006
Thermus thermophilus, Thermus thermophilus HB8, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Huang, L.; Pookanjanatavip, M.; Gu, X.; Santi, D.V.
A conserved aspartate of tRNA pseudouridine synthase is essential for activity and a probable nucleophilic catalyst
Biochemistry
37
344-351
1998
Escherichia coli, Escherichia coli (P07649)
Tsui, H.C.; Arps, P.J.; Connolly, D.M.; Winkler, M.E.
Absence of hisT-mediated tRNA pseudouridylation results in a uracil requirement that interferes with Escherichia coli K-12 cell division
J. Bacteriol.
173
7395-7400
1991
Escherichia coli K-12
Turnbough, C.L.Jr.; Neill, R.J.; Landsberg, R.; Ames, B.N.
Pseudouridylation of tRNAs and its role in regulation in Salmonella typhimurium
J. Biol. Chem.
254
5111-5119
1979
Salmonella enterica subsp. enterica serovar Typhimurium
Zhao, X.; Horne, D.A.
The role of cysteine residues in the rearrangement of uridine to pseudouridine catalyzed by pseudouridine synthase I
J. Biol. Chem.
272
1950-1955
1997
Escherichia coli
Ahn, K.S.; Ha, U.; Jia, J.; Wu, D.; Jin, S.
The truA gene of Pseudomonas aeruginosa is required for the expression of type III secretory genes
Microbiology
150
39-47
2004
Pseudomonas aeruginosa (O87016)
Hepfer, C.E.; Arnold-Croop, S.; Fogell, H.; Steudel, K.G.; Moon, M.; Roff, A.; Zaikoski, S.; Rickman, A.; Komsisky, K.; Harbaugh, D.L.; Lang, G.I.; Keil, R.L.
DEG1, encoding the tRNA:pseudouridine synthase Pus3p, impacts HOT1-stimulated recombination in Saccharomyces cerevisiae
Mol. Genet. Genomics
274
528-538
2005
Saccharomyces cerevisiae (P31115), Saccharomyces cerevisiae
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