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5.4.4.7: hydroperoxy icosatetraenoate isomerase

This is an abbreviated version!
For detailed information about hydroperoxy icosatetraenoate isomerase, go to the full flat file.

Word Map on EC 5.4.4.7

Reaction

a hydroperoxyicosatetraenoate
=
a hydroxyepoxyicosatrienoate

Synonyms

ALOXE3, eLOX-3, eLOX3, epidermal lipoxygenase-3, epidermal LOX type 3, hepoxilin synthase

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.4 Transferring hydroxy groups
                5.4.4.7 hydroperoxy icosatetraenoate isomerase

Substrates Products

Substrates Products on EC 5.4.4.7 - hydroperoxy icosatetraenoate isomerase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(12R)-HPETE
(8R)-hydroxy-(11R,12R)- epoxyeicosa-(5Z,9E,14Z)-trienoic acid
show the reaction diagram
-
preferred substrate
-
-
?
(12R)-HPETE
(8R)-hydroxy-(11R,12R)-epoxyeicosa-(5Z,9E,14Z)-trienoic acid
show the reaction diagram
-
-
-
-
?
(12R)-HPETE
(8R)-hydroxy-(11R,12R)-epoxyeicosa-(5Z,9E,14Z)-trienoic acid + 12-oxoeicosatetraenoic acid
show the reaction diagram
-
preferred substrate
2:1 ratio
-
?
(12R)-HPETE
?
show the reaction diagram
(12S)-HPETE
(10R)-hydroxy-(11S,12S)-epoxyeicosa-(5Z,8Z,14Z)-trienoic acid + (8R)-hydroxy-(11S,12S)-epoxyeicosa-(5Z,9E,14Z)-trienoic acid
show the reaction diagram
-
-
-
-
?
(12S)-HPETE
?
show the reaction diagram
-
-
-
-
?
(15S)-HPETE
(13R)-hydroxy-(14S,15S)-epoxyeicosa-(5Z,8Z,11Z)-trienoic acid
show the reaction diagram
-
-
-
-
?
(15S)-HPETE
15-oxoeicosa-(5Z,8Z,11Z,13E)-tetraenoic acid
show the reaction diagram
-
-
-
-
?
(15S)-HPETE
?
show the reaction diagram
-
-
-
-
?
(5S)-HPETE
(7R)-hydroxy-(5S,6S)-epoxyeicosa-(8Z,11Z,14Z)-trienoic acid
show the reaction diagram
(8R)-HPETE
8-KETE
show the reaction diagram
(8R)-HPETE
?
show the reaction diagram
-
-
-
-
?
(8S)-HPETE
(10R)-hydroxy-(8S,9S)-epoxyeicosa-(5Z,11Z,14Z)-trienoic acid
show the reaction diagram
additional information
?
-
-
linoleic, arachidonic, and eicosapentaenoic acids, the methyl esters of arachidonic acid and linoleic acid, arachidonyl phosphatidylcholine, anandamide, and the cholesteryl ester of arachidonic acid are no substrates
-
-
?