5.4.4.2: isochorismate synthase
This is an abbreviated version!
For detailed information about isochorismate synthase, go to the full flat file.
Word Map on EC 5.4.4.2
-
5.4.4.2
-
corticosteroid
-
inhaled
-
asthma
-
children
-
pulmonary
-
long-acting
-
airway
-
labas
-
asthmatic
-
agonist
-
bronchodilator
-
placebo
-
fluticasone
-
eosinophil
-
expiratory
-
prescript
-
short-acting
-
double-blind
-
physician
-
bronchial
-
beta2-agonists
-
budesonide
-
spirometry
-
montelukast
-
add-on
-
wheezing
-
randomised
-
ketanserin
-
5-hydroxytryptamine
-
leukotriene
-
once-daily
-
muscarinic
-
monotherapy
-
salmeterol
-
sputum
-
5-ht-induced
-
urodynamic
-
parallel-group
-
methysergide
-
intercostal
-
fixed-dose
-
immunochromatographic
-
self-management
-
ondansetron
-
incontinence
-
real-life
-
drug development
-
8-oh-dpat
-
datalink
-
agriculture
-
airflow
-
run-in
- 5.4.4.2
-
corticosteroid
-
inhaled
- asthma
- children
- pulmonary
-
long-acting
- airway
-
labas
-
asthmatic
- agonist
-
bronchodilator
-
placebo
-
fluticasone
-
eosinophil
-
expiratory
-
prescript
-
short-acting
-
double-blind
-
physician
- bronchial
-
beta2-agonists
-
budesonide
-
spirometry
- montelukast
-
add-on
-
wheezing
-
randomised
- ketanserin
- 5-hydroxytryptamine
-
leukotriene
-
once-daily
-
muscarinic
-
monotherapy
- salmeterol
- sputum
-
5-ht-induced
-
urodynamic
-
parallel-group
- methysergide
-
intercostal
-
fixed-dose
-
immunochromatographic
-
self-management
- ondansetron
- incontinence
-
real-life
- drug development
-
8-oh-dpat
-
datalink
- agriculture
-
airflow
-
run-in
Reaction
Synonyms
Amonabactin, AtICS1, AtICS2, DhbC, EC 5.4.99.6, Eds16, EntC, ICS, ICS1, ICS1 gene product, ICS2, IcsI, isochorismatase, isochorismate hydroxymutase, isochorismate mutase, isochorismate mutase 1, isochorismate mutase 2, isochorismate synthase, isochorismate synthase 1, isochorismate synthase 1, chloroplastic, isochorismate synthase 2, chloroplastic, Isochorismic synthase, MbtI, menaquinone-specific isochorismate synthase, MenF, PchA, salicylate biosynthesis isochorismate synthase, salicylate synthase, Sid2, Synthase, isochorismate
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 5.4.4.2 - isochorismate synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
?
-
two different isochorismate mutases, one is involved in the biosynthesis of the respiratory chain component menaquinone, MedF, and the other is involved in the synthesis of siderophore 2,3-dihydroxybenzoate, DhbC
-
-
?
Chorismate
?
-
the first enzyme involved in the biosynthesis of the powerful iron-chelating agent enterobactin
-
-
?
Chorismate
?
-
first committed step in the biosynthesis of menaquinone
-
-
?
Chorismate
?
-
enzyme catalyzes the pivotal step in enterobactin and menaquinone biosynthesis
-
-
?
Chorismate
Isochorismate
-
reaction operates near equilibrium, equilibrium constant is 0.89. Enzyme does not convert chorismate directly to salicylic acid
-
r
Chorismate
Isochorismate
alternative pathway to produce salicyl acid in response to pathogens
-
-
?
Chorismate
Isochorismate
-
involved in biosynthesis of salicylic acid
-
-
?
Chorismate
Isochorismate
-
not reversible, isochorismate synthase involved in enterobactin biosynthesis, MenF
-
?
Chorismate
Isochorismate
-
r, isochorismate synthase involved in menaquinone biosynthesis, EntC
-
?
Chorismate
Isochorismate
first enzyme of pyochelin biosynthesis
-
r
?
-
ICS2 participates in the synthesis of SA, but in limited amounts that become clearly detectable only when ICS1 is lacking
-
-
?
additional information
?
-
isozyme ICS1 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
isozyme ICS1 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
-
isozyme ICS1 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
isozyme ICS2 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
isozyme ICS2 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
-
isozyme ICS2 does not act as isochorismate pyruvate lyase (IPL, EC 4.2.99.21) and bifunctional salicylate synthase, it does not convert chorismate into salicylate
-
-
?
additional information
?
-
-
the enzyme is essential for siderohore biosynthesis, first step in salicylate production
-
-
?
additional information
?
-
-
the bifunctional salicylate synthase converts chorismate into salicylate through a two-step reaction, exhibiting both isochorismate synthase (EC 5.4.4.2) and isochorismate lyase (EC 4.2.99.21) activities
-
-
?
additional information
?
-
the bifunctional salicylate synthase converts chorismate into salicylate through a two-step reaction, exhibiting both isochorismate synthase (EC 5.4.4.2) and isochorismate lyase (EC 4.2.99.21) activities
-
-
?
additional information
?
-
-
the bifunctional salicylate synthase converts chorismate into salicylate through a two-step reaction, exhibiting both isochorismate synthase (EC 5.4.4.2) and isochorismate lyase (EC 4.2.99.21) activities
-
-
?
additional information
?
-
ICS enzyme is also required for salicylic acid biosynthesis
-
-
?
additional information
?
-
-
ICS enzyme is also required for salicylic acid biosynthesis
-
-
?
additional information
?
-
-
the bifunctional salicylate synthase converts chorismate into salicylate through a two-step reaction, exhibiting both isochorismate synthase (EC 5.4.4.2) and isochorismate lyase (EC 4.2.99.21) activities
-
-
?
additional information
?
-
-
the bifunctional salicylate synthase converts chorismate into salicylate through a two-step reaction, exhibiting both isochorismate synthase (EC 5.4.4.2) and isochorismate lyase (EC 4.2.99.21) activities
-
-
?