5.4.4.2: isochorismate synthase
This is an abbreviated version!
For detailed information about isochorismate synthase, go to the full flat file.
Word Map on EC 5.4.4.2
-
5.4.4.2
-
corticosteroid
-
inhaled
-
asthma
-
children
-
pulmonary
-
long-acting
-
airway
-
labas
-
asthmatic
-
agonist
-
bronchodilator
-
placebo
-
fluticasone
-
eosinophil
-
expiratory
-
prescript
-
short-acting
-
double-blind
-
physician
-
bronchial
-
beta2-agonists
-
budesonide
-
spirometry
-
montelukast
-
add-on
-
wheezing
-
randomised
-
ketanserin
-
5-hydroxytryptamine
-
leukotriene
-
once-daily
-
muscarinic
-
monotherapy
-
salmeterol
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sputum
-
5-ht-induced
-
urodynamic
-
parallel-group
-
methysergide
-
intercostal
-
fixed-dose
-
immunochromatographic
-
self-management
-
ondansetron
-
incontinence
-
real-life
-
drug development
-
8-oh-dpat
-
datalink
-
agriculture
-
airflow
-
run-in
- 5.4.4.2
-
corticosteroid
-
inhaled
- asthma
- children
- pulmonary
-
long-acting
- airway
-
labas
-
asthmatic
- agonist
-
bronchodilator
-
placebo
-
fluticasone
-
eosinophil
-
expiratory
-
prescript
-
short-acting
-
double-blind
-
physician
- bronchial
-
beta2-agonists
-
budesonide
-
spirometry
- montelukast
-
add-on
-
wheezing
-
randomised
- ketanserin
- 5-hydroxytryptamine
-
leukotriene
-
once-daily
-
muscarinic
-
monotherapy
- salmeterol
- sputum
-
5-ht-induced
-
urodynamic
-
parallel-group
- methysergide
-
intercostal
-
fixed-dose
-
immunochromatographic
-
self-management
- ondansetron
- incontinence
-
real-life
- drug development
-
8-oh-dpat
-
datalink
- agriculture
-
airflow
-
run-in
Reaction
Synonyms
Amonabactin, AtICS1, AtICS2, DhbC, EC 5.4.99.6, Eds16, EntC, ICS, ICS1, ICS1 gene product, ICS2, IcsI, isochorismatase, isochorismate hydroxymutase, isochorismate mutase, isochorismate mutase 1, isochorismate mutase 2, isochorismate synthase, isochorismate synthase 1, isochorismate synthase 1, chloroplastic, isochorismate synthase 2, chloroplastic, Isochorismic synthase, MbtI, menaquinone-specific isochorismate synthase, MenF, PchA, salicylate biosynthesis isochorismate synthase, salicylate synthase, Sid2, Synthase, isochorismate
ECTree
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KI Value
KI Value on EC 5.4.4.2 - isochorismate synthase
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2
(4R,5R)-4-hydroxy-5-carboxymethoxy-cyclohex-1-enecarboxylate
-
IC50 above 2.0 mM
2
(4R,5R)-5-(2-carboxy-allyloxy)-4-hydroxy-cyclohex-1-enecarboxylate
-
IC50 above 2.0 mM
0.000053
(4R,5R,6S)-6-amino-5-[(1-carboxyethenyl)oxy]-4-hydroxycyclohex-1-ene-1-carboxylic acid
pH and temperature not specified in the publication
0.00005
(4R,5R,6S)-6-ammonio-5-[(1-carboxylatoethenyl)oxy]-4-hydroxycyclohex-1-ene-1-carboxylate
-
-
2
(4R,5R,7R)-5-(1-carboxy-ethoxy)-4-hydroxy-cyclohex-1-enecarboxylate
-
IC50 above 2.0 mM
2
(4R,5R,7S)-5-(1-carboxy-ethoxy)-4-hydroxy-cyclohex-1-enecarboxylate
-
IC50 above 2.0 mM
0.1
(4R,5S,6R)-4-amino-5-(2-carboxyethyl)-6-hydroxycyclohex-1-ene-1-carboxylic acid
-
pH 8.0, 37°C
-
0.00046
(4R,5S,6S)-4-amino-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohex-1-ene-1-carboxylic acid
pH and temperature not specified in the publication
0.00045
(4R,5S,6S)-4-ammonio-5-[(1-carboxylatoethenyl)oxy]-6-hydroxycyclohex-1-ene-1-carboxylate
-
-
0.00036
(4R,5S,6S)-5-[(1-carboxyethenyl)oxy]-4,6-dihydroxycyclohex-1-ene-1-carboxylic acid
pH and temperature not specified in the publication
0.00036
(4R,5S,6S)-5-[(1-carboxylatoethenyl)oxy]-4,6-dihydroxycyclohex-1-ene-1-carboxylate
-
-
0.011
3-[[(1Z)-1-carboxyprop-1-en-1-yl]oxy]-2-hydroxybenzoic acid
-
pH 8.0, 37°C
0.03
pH and temperature not specified in the publication, inhibition of isochorismate synthase activity
0.16
(4R,5R)-5-[(1-carboxyethenyl)oxy]-4-hydroxycyclohex-1-ene-1-carboxylic acid
pH and temperature not specified in the publication, inhibition of salicylate synthase activity