5.4.3.8: glutamate-1-semialdehyde 2,1-aminomutase

This is an abbreviated version!
For detailed information about glutamate-1-semialdehyde 2,1-aminomutase, go to the full flat file.

Word Map on EC 5.4.3.8

5.4.3.8

chlorophyll

5-aminolevulinic

tetrapyrrole

glutamyl-trna

delta-aminolevulinic

synechococcus

gabaculine

hema

4,5-diaminovalerate

trnaglu

4,5-dioxovalerate

aldimine

glutr

five-carbon

glutamyl-trnaglu

trna-dependent

3-amino-2,3-dihydrobenzoic

chelatase

mg-chelatase

Reaction

Synonyms

Aminotransferase, glutamate semialdehyde, AtGSA1, EC 2.7.2.13, Glutamate 1-semialdehyde aminotransferase, glutamate-1-semialdehyde amino-transferase, glutamate-1-semialdehyde aminomutase, Glutamate-1-semialdehyde aminotransferase, glutamate-1-semialdehyde-2,1-aminomutase, glutamate-1-semialdehyde-aminomutase, GSA, GSA aminotransferase, GSA-AT, GSA1, GSAM, GSAT, HemL, PA4088, protein PA4088

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.3 Transferring amino groups

5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase

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Results	in table
3	Activating Compound
32180	AA Sequence
1	CAS Registry Number
17	Cloned(Commentary)
25	Cofactor
8	Crystallization (Commentary)
2	Expression
8	General Information
2	IC50 Value
23	Inhibitors
8	KM Value [mM]
5	Localization
2	Metals/Ions
17	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
74	Organism
7	Pathway
50	PDB ID
3	pH Optimum
2	pH Range
8	Protein Variants
16	Purification (Commentary)
8	Reaction
2	Reaction Type
47	Reference
7	Source Tissue
8	Specific Activity [micromol/min/mg]
68	Substrates and Products (Substrate)
19	Subunits
39	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Turnover Number [1/s]

Purification

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Purification on EC 5.4.3.8 - glutamate-1-semialdehyde 2,1-aminomutase

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6 entries

nickel-chelating resin column chromatography and Superdex 200 gel filtration

partial

recombinant enzyme

recombinant GSA-AT

recombinant GSAT

recombinant His-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration

Pseudomonas aeruginosa

Q9HWU0

747005

recombinant His6-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography, removal of the His-tag through TEV protease, followed by gel filtration, and ultrafiltration

Arabidopsis thaliana

P42799

746660

wild-type enzyme and gabaculine-resistant mutant enzyme

Synechococcus sp.

3430